J Neugarten, L Golestaneh - Mayo Clinic Proceedings, 2019 - Elsevier
The role that sex plays in the development and progression of chronic kidney disease remains a subject of controversy. The lack of clarity in this important area reflects complex …
S Silbiger, J Neugarten - Gender medicine, 2008 - Elsevier
Background: Gender affects the incidence, prevalence, and progression of renal disease. In animal models of the disease, female sex appears to modify the course of progression …
SC Freixas, M Kotlyar, CM McEvoy… - Journal of the …, 2022 - journals.lww.com
Background: Diabetic Kidney Disease (DKD) is recongnized as the leading cause of Chronic Kidney Disease (CKD). Male sex is a risk factor for CKD, and is generally …
J Neugarten, B Kasiske, SR Silbiger, JR Nyengaard - Nephron, 2002 - karger.com
Aims: There are few data examining differences in renal structure between the sexes. Elucidation of the mechanisms responsible for the observed effects of sex on the …
C Conte, G Antonelli, ME Melica, M Tarocchi… - International Journal of …, 2023 - mdpi.com
Chronic kidney disease (CKD) is a constantly growing global health burden, with more than 840 million people affected worldwide. CKD presents sex disparities in the pathophysiology …
M Jankowska, MJ Soler, KI Stevens… - Clinical Kidney …, 2023 - academic.oup.com
Throughout the history of nephrology, little attention has been paid to the sex and gender differences in kidney disease. This lack of awareness prevents optimal diagnosis and …
K Denton, C Baylis - American Journal of Physiology …, 2007 - journals.physiology.org
IT IS WELL ESTABLISHED THAT cardiovascular disease is a leading cause of death in developed countries, but it is less well known that more women than men die of …
Abstract Knowledge of the transcriptional programs underpinning the functions of human kidney cell populations at homeostasis is limited. We present a single-cell perspective of …
M Scholz, K Horn, J Pott, M Wuttke, A Kühnapfel… - Nature …, 2024 - nature.com
X-chromosomal genetic variants are understudied but can yield valuable insights into sexually dimorphic human traits and diseases. We performed a sex-stratified cross-ancestry …