The liver plays a crucial role in a variety of physiological processes. Sexual dimorphism is
markedly defined in liver disorders, such as fatty liver diseases and liver cancer, but barely …

METHODS: Renal IRI was performed in female and male pigs and mice to identify genes of
translational relevance for humans that could be eventually studied in mouse models. Pre …

Determining the epigenetic program that generates unique cell types in the kidney is critical
for understanding cell-type heterogeneity during tissue homeostasis and injury response …

Metabolic homeostasis operates differently in men and women. This sex asymmetry is the
result of evolutionary adaptations that enable women to resist loss of energy stores and …

Renal cell carcinoma (RCC) has an undisputed genetic component and a stable 2: 1 male to
female sex ratio in its incidence across populations, suggesting possible sexual dimorphism …

The kidney is one of the most energy-demanding organs in the human body, and the
maintenance of mitochondrial homeostasis is central to kidney function. Recent advances …

The kidneys are essential organs that help maintain homeostasis, and their function is
regulated by the neural system. Despite the anatomical multi-synaptic connection between …

Background: Kidney disease is highly heritable. Understanding how genetic variants
influence kidney function can reveal molecular pathways underlying kidney disease …

Men are more frequently diagnosed with kidney cancer than women, with a more aggressive
histology, larger tumors, a higher grade and stage, and worse oncological outcomes …

Background: The sexually dimorphic differentiation of the bipotential gonad into testis or
ovary initiates the sexually dimorphic development of mammals and leads to divergent …