The basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family comprises many transcription
factors, found throughout all three kingdoms of life; bHLH/PAS members “sense” …

The aryl hydrocarbon receptor (AHR) is a nuclear receptor that modulates the response to
environmental stimuli. It was recognized historically for its role in toxicology but, in recent …

The induction of expression of genes for xenobiotic metabolizing enzymes in response to
chemical insult is an adaptive response found in most organisms. In vertebrates, the AhR is …

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that
regulates the transcription of certain key enzymes involved in the metabolism of xenobiotic …

We delineate a mechanism by which dioxin (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin or TCDD)-
mediated formation of the aryl hydrocarbon receptor (AhR) DNA binding complex is …

The structure-dependent aryl hydrocarbon (Ah) receptor agonist and antagonist activities of
the following substituted flavones were investigated: flavone, 4′-methoxy-, 4′-amino-, 4 …

The Ah receptor is a ligand-dependent transcription factor that mediates the biological and
toxic effects of polycyclic aromatic hydrocarbons and halogenated aromatic hydrocarbons …

Discovered as a modulator of the toxic response to environmental pollutants, aryl
hydrocarbon receptor (AhR) has recently gained attention for its involvement in various …

Aryl hydrocarbon receptor (AHR) research has shifted from exploring dioxin toxicity to
elucidation of physiologic AHR functions. Control of AHR functions is challenged by the fact …

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that mediates
the toxic and biological effects of a variety of chemicals. Although halogenated and …