Alternative splicing represents an important level of the regulation of gene function in
eukaryotic organisms. It plays a critical role in virtually every biological process within an …

Alternative splicing of mRNA precursors provides an important means of genetic control and
is a crucial step in the expression of most genes. Alternative splicing markedly affects human …

Alternative splicing plays critical roles in differentiation, development, and disease and is a
major source for protein diversity in higher eukaryotes. Analysis of alternative splicing …

Alternative splicing greatly expands the transcriptomic and proteomic diversities related to
physiological and developmental processes in higher eukaryotes. Splicing of long …

Alternative splicing is a process by which multiple messenger RNAs (mRNAs) are generated
from a single pre-mRNA, resulting in functionally distinct protein products. This is …

The generation of protein coding mRNAs from pre-mRNA is a fundamental biological
process that is required for gene expression. Alternative pre-mRNA splicing is responsible …

Alternative splicing is one of the most important mechanisms to generate a large number of
mRNA and protein isoforms from the surprisingly low number of human genes. Unlike …

In violation of the'one gene, one polypeptide'rule, alternative splicing allows individual
genes to produce multiple protein isoforms—thereby playing a central part in generating …

The precise splicing outcome of a transcribed gene is controlled by complex interactions
between cis regulatory splicing signals and trans‐acting regulators. In higher eukaryotes …

The first wave of bioinformatic studies that followed genome and complementary DNA
sequencing projects revealed that alternative splicing of messenger RNA precursors (pre …