[HTML][HTML] Virus-host interactome and proteomic survey reveal potential virulence factors influencing SARS-CoV-2 pathogenesis

J Li, M Guo, X Tian, X Wang, X Yang, P Wu, C Liu… - Med, 2021 - cell.com
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a global public health …

COVID‐19: Consider IL‐6 receptor antagonist for the therapy of cytokine storm syndrome in SARS‐CoV‐2 infected patients

C Chakraborty, AR Sharma… - Journal of medical …, 2020 - Wiley Online Library
COVID‐19 leads to mortality of several patients and the cytokine storm is reportedly critical
in the patients. To reduce the cytokine storm, we would like to propose the interleukin (IL) 6 …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), which began in Wuhan, China, in
December 2019, has caused a large global pandemic and poses a serious threat to public …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

[HTML][HTML] SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO

J Wu, Y Shi, X Pan, S Wu, R Hou, Y Zhang, T Zhong… - Cell reports, 2021 - cell.com
Summary Coronavirus disease 2019 (COVID-19) is a current global health threat caused by
the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional …

AM Gamage, KS Tan, WOY Chan, J Liu, CW Tan… - PLoS …, 2020 - journals.plos.org
The novel coronavirus SARS-CoV-2 is the causative agent of Coronavirus Disease 2019
(COVID-19), a global healthcare and economic catastrophe. Understanding of the host …

Immune evasion via SARS-CoV-2 ORF8 protein?

MD Park - Nature Reviews Immunology, 2020 - nature.com
In this preprint, Zhang et al. elucidate a potential immune evasion strategy involving the
SARS-CoV-2 ORF8 protein. They show that expression of ORF8, which directly binds to …

[PDF][PDF] CXCL10 an important chemokine associated with cytokine storm in COVID-19 infected patients.

N Zhang, YD Zhao, XM Wang - European Review for Medical & …, 2020 - europeanreview.org
OBJECTIVE: The specific mechanism of cytokine storm in COVID-19 infected patients is not
clear. This study aims to identify the key genes that cause cytokine storm in COVID-19 …

Advances in the research of mechanism and related immunotherapy on the cytokine storm induced by coronavirus disease 2019

C Chen, XR Zhang, ZY Ju, WF He - Zhonghua shao shang za zhi …, 2020 - europepmc.org
Coronavirus disease 2019 (COVID-19) has seriously affected the safety of patients and
social stability. Some COVID-19 patients in the later stage of disease may develop into acute …

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
Corona Virus Disease 2019 (COVID-19) pandemic is rapidly spreading all over the world.
Excessive immune responses trigger life-threatening cytokine release syndrome (CRS) …