Mediation of endoplasmic reticulum stress and NF-κB signaling pathway in DINP-exacerbated allergic asthma: A toxicological study with Balb/c mice

F Lei, Y Wu, C Li, B Yan, S Chen, Q Peng… - Journal of Hazardous …, 2023 - Elsevier
Epidemiological evidence indicates a significant relationship between exposure to
diisononyl phthalate and allergic asthma. Despite this, the mechanism underlying this …

Exposure to formaldehyde and diisononyl phthalate exacerbate neuroinflammation through NF-κB activation in a mouse asthma model

J Duan, J Kang, W Qin, T Deng, H Liu, B Li… - Ecotoxicology and …, 2018 - Elsevier
Diisononyl phthalate (DINP) and formaldehyde both are associated with asthma and
allergies. However, it is unclear about the adverse effect of DINP and formaldehyde …

Diisononyl phthalate induces asthma via modulation of Th1/Th2 equilibrium

YH Hwang, MJ Paik, ST Yee - Toxicology letters, 2017 - Elsevier
Diisononyl phthalate (DINP), a member of the phthalate family, is used to plasticize polyvinyl
chloride (PVC). This chemical is known to enhance airway inflammation in the OVA-induced …

The IL-31/TRPV1 pathway mediates allergic asthma exacerbated by DINP dermal exposure in OVA-sensitized Balb/c mice

Q Peng, Y Wu, Y Li, C Lu, R Yao, S Hu, N Ma… - Science of the Total …, 2024 - Elsevier
Background The potential role of dermal exposure diisononyl phthalate (DINP) as an
adjuvant in allergic inflammation and asthma has been suggested. However, the current …

Exposure to diisodecyl phthalate exacerbated Th2 and Th17-mediated asthma through aggravating oxidative stress and the activation of p38 MAPK

W Qin, T Deng, H Cui, Q Zhang, X Liu, X Yang… - Food and Chemical …, 2018 - Elsevier
Diisodecyl phthalate (DIDP) is considered to be one of the less toxic phthalates. However
epidemiological studies suggest that DIDP is associated with the occurrence of asthma. The …

Exposure to a combination of formaldehyde and DINP aggravated asthma-like pathology through oxidative stress and NF-κB activation

J Kang, J Duan, J Song, C Luo, H Liu, B Li, X Yang… - Toxicology, 2018 - Elsevier
Several epidemiological and experimental studies indicate a positive association between
exposure to formaldehyde or phthalates and allergic asthma. However, nothing is yet known …

Dibutyl phthalate induces allergic airway inflammation in rats via inhibition of the Nrf2/TSLP/JAK1 pathway

X Wang, B Han, P Wu, S Li, Y Lv, J Lu, Q Yang, J Li… - Environmental …, 2020 - Elsevier
Dibutyl phthalate (DBP), an important plastic contaminant in the environment, is known to
cause organ toxicity. Although current research has shown that DBP-induced organ toxicity …

[HTML][HTML] Diisononyl phthalate aggravates allergic dermatitis by activation of NF-kB

J Kang, J Song, S Shen, B Li, X Yang, M Chen - Oncotarget, 2016 - ncbi.nlm.nih.gov
Several epidemiological studies have suggested a possible link between exposure to
Diisononyl phthalate (DINP) and the development of allergies. These findings remain …

Mediation of the JNC/ILC2 pathway in DBP-exacerbated allergic asthma: A molecular toxicological study on neuroimmune positive feedback mechanism

X Xie, Y Li, B Yan, Q Peng, R Yao, Q Deng, J Li… - Journal of Hazardous …, 2024 - Elsevier
Background Dibutyl phthalate (DBP), a commonly used plasticizer, has been found to be
strongly linked to a consistently high prevalence of allergic diseases, particularly allergic …

Dibutyl phthalate aggravated asthma-like symptoms through oxidative stress and increasing calcitonin gene-related peptide release

S Zhou, M Han, Y Ren, X Yang, L Duan, Y Zeng… - … and Environmental Safety, 2020 - Elsevier
Dibutyl phthalate (DBP) is one of the most ubiquitous phthalate esters found in everyday
products, and is receiving increased attention as an immunologic adjuvant. However …