I Tanniche, B Behkam - Journal of Biological Engineering, 2023 - Springer
Sensitive and minimally invasive medical diagnostics are essential to the early detection of diseases, monitoring their progression and response to treatment. Engineered bacteria as …
Bacteria are emerging as living drugs to treat a broad range of disease indications. However, the inherent advantages of these replicating and immunostimulatory therapies …
Naturally occurring microorganisms have been used therapeutically for over a century, but the advent of modern techniques for genetic manipulation has created unprecedented …
Y Zhou, Y Han - Engineering Microbiology, 2022 - Elsevier
The development of drug delivery vehicles is in significant demand in the context of precision medicine. With the development of synthetic biology, the use of genetically …
IY Hwang - Current Opinion in Systems Biology, 2023 - Elsevier
In recent years, synthetic biology has provided many engineering approaches to reprogram and engineer cells in diverse applications including the development of novel therapeutics …
V Raman, CP Deshpande, S Khanduja, LM Howell… - Cell Host & Microbe, 2023 - cell.com
Many systemically administered cancer therapies exhibit dose-limiting toxicities that reduce their effectiveness. To increase efficacy, bacterial delivery platforms have been developed …
L Rong, Q Lei, XZ Zhang - ACS Applied Bio Materials, 2020 - ACS Publications
Bacteria possess many unique properties in treating cancer that are unachievable with standard methods, including specific tumor targeting, deep tissue penetration, and …
R Omer, MZ Mohsin, A Mohsin, BS Mushtaq… - … in Bioengineering and …, 2022 - frontiersin.org
Future advances in therapeutics demand the development of dynamic and intelligent living materials. The past static monofunctional materials shall be unable to meet the requirements …
T Gong, J Wu - Expert Opinion on Drug Delivery, 2023 - Taylor & Francis
Introduction Cancer mortality worldwide highlights the urgency for advanced therapeutic methods to fill the gaps in conventional cancer therapies. Bacteriotherapy is showing great …