[HTML][HTML] A scheme for inferring viral-host associations based on codon usage patterns identifies the most affected signaling pathways during COVID-19
Understanding the molecular mechanism of COVID-19 pathogenesis helps in the rapid
therapeutic target identification. Usually, viral protein targets host proteins in an organized …
therapeutic target identification. Usually, viral protein targets host proteins in an organized …
Protein sequence models for prediction and comparative analysis of the SARS-CoV-2—human interactome
Viruses such as the novel coronavirus, SARS-CoV-2, that is wreaking havoc on the world,
depend on interactions of its own proteins with those of the human host cells. Relatively …
depend on interactions of its own proteins with those of the human host cells. Relatively …
Bioinformatics-Based Approaches to Study Virus–Host Interactions During SARS-CoV-2 Infection
As the knowledge of biomolecules is increasing from the last decades, it is helping the
researchers to understand the unsolved issues regarding virology. Recent technologies in …
researchers to understand the unsolved issues regarding virology. Recent technologies in …
Computational identification of human biological processes and protein sequence motifs putatively targeted by SARS-COV-2 proteins using protein–protein interaction …
R Nadeau, S Shahryari Fard, A Scheer… - Journal of proteome …, 2020 - ACS Publications
While the COVID-19 pandemic is causing important loss of life, knowledge of the effects of
the causative SARS-CoV-2 virus on human cells is currently limited. Investigating protein …
the causative SARS-CoV-2 virus on human cells is currently limited. Investigating protein …
Analyzing host-viral interactome of sars-cov-2 for identifying vulnerable host proteins during covid-19 pathogenesis
The development of therapeutic targets for COVID-19 relies on understanding the molecular
mechanism of pathogenesis. Identifying genes or proteins involved in the infection …
mechanism of pathogenesis. Identifying genes or proteins involved in the infection …
[HTML][HTML] The analysis on the human protein domain targets and host-like interacting motifs for the MERS-CoV and SARS-CoV/CoV-2 infers the molecular mimicry of …
The MERS-CoV, SARS-CoV, and SARS-CoV-2 are highly pathogenic viruses that can
cause severe pneumonic diseases in humans. Unfortunately, there is a non-available …
cause severe pneumonic diseases in humans. Unfortunately, there is a non-available …
[HTML][HTML] Identification of potential therapeutic targets for COVID-19 through a structural-based similarity approach between SARS-CoV-2 and its human host proteins
Background: The COVID-19 pandemic caused by SARS-CoV-2 has led to millions of deaths
worldwide, and vaccination efficacy has been decreasing with each lineage, necessitating …
worldwide, and vaccination efficacy has been decreasing with each lineage, necessitating …
[HTML][HTML] Role of ribosomal pathways and comorbidity in COVID-19: Insight from SARS-CoV-2 proteins and host proteins interaction network analysis
The COVID-19 pandemic has become a significant global issue in terms of public health.
While it is largely associated with respiratory complications, recent reports indicate that …
While it is largely associated with respiratory complications, recent reports indicate that …
[HTML][HTML] Network neighbors of viral targets and differentially expressed genes in COVID-19 are drug target candidates
The COVID-19 pandemic is raging. It revealed the importance of rapid scientific
advancement towards understanding and treating new diseases. To address this challenge …
advancement towards understanding and treating new diseases. To address this challenge …
[HTML][HTML] Atlas of interactions between SARS-CoV-2 macromolecules and host proteins
G Li, Z Tang, W Fan, X Wang, L Huang, Y Jia, M Wang… - Cell Insight, 2023 - Elsevier
The proteins and RNAs of viruses extensively interact with host proteins after infection. We
collected and reanalyzed all available datasets of protein-protein and RNA-protein …
collected and reanalyzed all available datasets of protein-protein and RNA-protein …