From next-generation sequencing to nanopore sequencing technology: paving the way to personalized genomic medicine

CS Ku, DH Roukos - Expert review of medical devices, 2013 - Taylor & Francis
Although the goal of US $1000 human genome sequencing will become a reality in a few
years, it is suggested that at present clinical analysis, interpretation and decision-making …

implementing whole genome sequencing (WGS) in clinical practice: advantages, challenges, and future perspectives

P Brlek, L Bulić, M Bračić, P Projić, V Škaro, N Shah… - Cells, 2024 - mdpi.com
The integration of whole genome sequencing (WGS) into all aspects of modern medicine
represents the next step in the evolution of healthcare. Using this technology, scientists and …

Sequencing of human genomes with nanopore technology

R Bowden, RW Davies, A Heger… - Nature …, 2019 - nature.com
Whole-genome sequencing (WGS) is becoming widely used in clinical medicine in
diagnostic contexts and to inform treatment choice. Here we evaluate the potential of the …

The evolution of nanopore sequencing

Y Wang, Q Yang, Z Wang - Frontiers in genetics, 2015 - frontiersin.org
The “1000Genome”projecthasbeendrawingincreasingattention….Nanoporesequencing,
thethird-generation,isbelievedtobeoneofthemostpromisingsequ…“ 1000 Genome” while the …

Applications and potentials of nanopore sequencing in the (epi) genome and (epi) transcriptome era

S Xie, AWS Leung, Z Zheng, D Zhang, C Xiao, R Luo… - The Innovation, 2021 - cell.com
Summary The Human Genome Project opened an era of (epi) genomic research, and also
provided a platform for the development of new sequencing technologies. During and after …

Nanopore sequencing: from imagination to reality

H Bayley - Clinical chemistry, 2015 - academic.oup.com
DNA sequencing and hence genomics have been transformed over the last decade by the
commercialization of inexpensive, massively parallel, short-read sequencing technology …

Next-generation sequencing: from basic research to diagnostics

KV Voelkerding, SA Dames, JD Durtschi - Clinical chemistry, 2009 - academic.oup.com
Background: For the past 30 years, the Sanger method has been the dominant approach
and gold standard for DNA sequencing. The commercial launch of the first massively …

Molecular diagnostics for personal medicine using a nanopore

UM Mirsaidov, D Wang, W Timp… - Wiley Interdisciplinary …, 2010 - Wiley Online Library
Semiconductor nanotechnology has created the ultimate analytical tool: a nanopore with
single molecule sensitivity. This tool offers the intriguing possibility of high‐throughput, low …

Portable nanopore-sequencing technology: Trends in development and applications

P Chen, Z Sun, J Wang, X Liu, Y Bai, J Chen… - Frontiers in …, 2023 - frontiersin.org
Sequencing technology is the most commonly used technology in molecular biology
research and an essential pillar for the development and applications of molecular biology …

Oxford Nanopore announcement sets sequencing sector abuzz

O Nanopore - Nat. Biotechnol, 2012 - nature.com
© 2012 Nature America, Inc. All rights reserved. 296 volume 30 number 4 APrIl 2012
NATURE BIoTECHNoloGy volume, nobody in their right mind would invest in a short …