H Miyawaki, M Ashraf - Circulation research, 1997 - Am Heart Assoc
We tested the hypothesis that elevation of [Ca2+] i during ischemic preconditioning (IPC) stimulates protein kinase C (PKC), which confers the protection against the ischemic injury …
W Zhang, F Lu, Y Zhao, L Wang, Y Tian, Z Pan… - Biochemical and …, 2007 - Elsevier
Protein kinase C (PKC) plays a role in cardioprotection through reduction of intracellular Ca2+ concentration [Ca2+] i during ischemic preconditioning (IPC). Cardioprotection against …
BS Cain, DR Meldrum, MD Xianzhong Meng… - The Annals of thoracic …, 1998 - Elsevier
Background. Ischemic stress and other protein kinase C (PKC)–linked receptor stimuli can induce rapid cardiac protection against ischemia-reperfusion injury. We and others have …
H Miyawaki, M Ashraf - American Journal of Physiology …, 1997 - journals.physiology.org
We tested the hypothesis that a transient increase in intracellular calcium concentration ([Ca2+] i) before prolonged ischemia triggers the activation of protein kinase C (PKC) …
K Yamamura, C Steenbergen… - American Journal of …, 2005 - journals.physiology.org
Activation of protein kinase C (PKC) is cardioprotective, but the mechanism (s) by which PKC mediates protection is not fully understood. Inasmuch as PKC has been well …
S Kawamura, KI Yoshida, T Miura… - American Journal …, 1998 - journals.physiology.org
Protein kinase C (PKC) plays an important role in mediating ischemic preconditioning (PC). However, the relationship between PKC isoforms and PC is still uncertain. We analyzed …
DR Meldrum, JC Cleveland Jr, BC Sheridan… - The Journal of Thoracic …, 1996 - Elsevier
Cardiac preconditioning is mediated by protein kinase C. Although endogenous calcium is a potent stimulus of protein kinase C, it remains unknown whether preischemic administration …
J An, SG Varadarajan, E Novalija… - American Journal of …, 2001 - journals.physiology.org
Ca+ loading during reperfusion after myocardial ischemia is linked to reduced cardiac function. Like ischemic preconditioning (IPC), a volatile anesthetic given briefly before …
K Node, M Kitakaze, H Sato, T Minamino… - Circulation, 1997 - Am Heart Assoc
Background Activation of protein kinase C plays an important role in ischemic preconditioning. Given that protein kinase C is activated by an increase in the intracellular …