This is a personal perspective on bipolar disorder, entirely written by a well-informed patient
who is a successful mental heath professional. The patient prefers to remain anonymous; …

Bipolar disorder (BD) is a chronic and often severe psychiatric illness characterized by
manic and depressive episodes. Among the most effective treatments, mood stabilizers …

Background Treatment in bipolar disorder (BD) is commonly applied as a multimodal
therapy based on decision algorithms that lack an integrative understanding of molecular …

The hopes for readily implementable precision medicine are high. For many complex
disorders, such as bipolar disorder, these hopes critically hinge on tangible successes in …

Personalized medicine (personalized psychiatry in a specific setting) is a new model
towards individualized care, in which knowledge from genomics and other omic pillars …

Bipolar disorder is characterized by pathological mood episodes, both mania and
depression. A series of genetic studies have demonstrated a high degree of heritability and …

The holistic approach of personalized medicine, merging clinical and molecular
characteristics to tailor the diagnostic and therapeutic path to each individual, is steadily …

Bipolar disorder (BD) is a lifelong severe psychiatric condition with high morbidity, disability
and excess mortality. The longitudinal clinical trajectory of BD is significantly modified by …

The lifetime prevalence of bipolar disorder is estimated to be about 2%. Epigenetics defines
regulatory mechanisms that determine relatively stable patterns of gene expression by …

Although Kraepelin described bipolar disorder (BD) to have a relatively good prognosis
(Kraepelin, 1921), more recent studies have clearly shown that this may only represent the …