JM Bergelson, NF St John, S Kawaguchi… - Cell adhesion and …, 1994 - Taylor & Francis
VLA-2, the α2β1 integrin, mediates cell adhesion to collagen and laminin, and is the receptor for the human pathogen echovirus 1. Because of its similarity to domains present in …
JM Edelman, BMC Chan, S Uniyal… - Cell Adhesion and …, 1994 - Taylor & Francis
Human VLA-2 (α2β1) mediates cellular adhesion to collagen and laminin and cell attachment by the human pathogen echovirus 1. We report here the cloning, sequencing …
JM Bergelson, BM Chan, RW Finberg… - The Journal of …, 1993 - Am Soc Clin Investig
The integrin VLA-2 mediates cell adhesion to collagen and laminin and also functions as a virus receptor, mediating cell surface attachment and infection by a human pathogen …
J Emsley, SL King, JM Bergelson… - Journal of Biological …, 1997 - ASBMB
We have determined the high resolution crystal structure of the I domain from the α-subunit of the integrin α2β1, a cell surface adhesion receptor for collagen and the human pathogen …
J Jokinen, DJ White, M Salmela, M Huhtala… - The EMBO …, 2010 - embopress.org
Conformational activation increases the affinity of integrins to their ligands. On ligand binding, further changes in integrin conformation elicit cellular signalling. Unlike any of the …
L Xing, M Huhtala, V Pietiäinen, J Käpylä… - Journal of biological …, 2004 - ASBMB
Integrins are cell surface receptors for several microbial pathogens including echovirus 1 (EV1), a picornavirus. Cryo-electron microscopy revealed that the functional domain (α 2 I) of …
SL King, JA Cunningham, RW Finberg… - Journal of …, 1995 - Am Soc Microbiol
The isolated I domain of the integrin VLA-2, produced as a bacterial fusion protein, specifically bound echovirus 1 and prevented virus attachment to cells. These results …
T Kamata, W Puzon, Y Takada - Journal of Biological Chemistry, 1994 - Elsevier
Integrin alpha 2 beta 1 is a cell surface adhesion receptor for collagen and echovirus 1. Here we localized the epitopes for anti-alpha 2 monoclonal antibodies using interspecies …