Angiogenesis, formation of new vessels from pre-existing ones, results from stimulation of
endothelial cells, which line the vessel wall. These cells will leave their resting state and …

Angiogenesis is the process in which new blood vessels grow by sprouting from established
ones. Blood vessel growth occurs in the embryo but rarely in the adult. Exceptions arise …

Fibroblast growth factors (FGFs) are considered angiogenic factors, yet the exact
relationship between FGF and vascular development in normal and pathological tissue has …

Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …

The dependence of tumor growth on the development of a neovasculature is well-
established [1]. After a tumor grows beyond 100 mm to 200 mm in size, diffusion alone is no …

Although fibroblast growth factors are potent angiogenic factors, they may indirectly control
neovascularization in concert with other growth factors. Thus, the unique role played by …

Angiogenic growth factors such as fibroblast growth factors (FGFs) and vascular endothelial
growth factors (VEGFs) are currently targets of intense efforts to inhibit deregulated blood …

The existence of angiogenic factors was initially postulated on the basis of the strong
neovascular response induced by transplanted tumors. Subsequently, it was shown that …

Angiogenesis, or formation of new blood vessels from pre-existing ones, is essential for
normal development and wound healing/reproductive functions in adults. Abnormal …

New blood vessel formation (angiogenesis) is a fundamental event in the process of tumor
growth and metastatic dissemination. Hence, the molecular basis of tumor angiogenesis has …