Meet biology's next big intellectual challenge. It's called systems biology, and the discipline
has begun to piece together the first detailed sketch of how cells process various …

Systems biology analyses in cancer are rapidly changing from merely descriptive efforts in
the high-throughput experimental works and overtly technical, calculation-centered studies …

Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …

Decades of focused cancer research have demonstrated the oncogenic process to be
frustratingly complex. Despite many triumphs in scientific and clinical understanding, we still …

With over two hundred types of cancer diagnosed to date, researchers the world over have
been forced to rapidly update their understanding of the biology of cancer. In fact, only the …

Cancer is a complex disease involving multiple mechanisms and critical players, at broad
genomic, transcriptional, translational and/or biochemical levels. One could envision …

Constructing, evaluating, and interpreting gene networks generally sits within the broader
field of systems biology, which continues to emerge rapidly, particular with respect to its …

In recent years it has become clear that carcinogenesis is a complex process, both at the
molecular and cellular levels. Understanding the origins, growth and spread of cancer …

Rather than a strictly formalized methodological framework, we here describe systems
biology as a flexible approach in which the modelling strategy used depends on a trade-off …

Praise for Computational Systems BiologyApproaches in Cancer Research:" Complex
concepts are written clearly and with informative illustrations and useful links. The book is …