Tumours are complex biological systems. No single type of molecular approach fully
elucidates tumour behaviour, necessitating analysis at multiple levels encompassing …

We are in the midst of a momentous change in biomedicine that is precipitated by an
explosion of genomic, molecular and clinical data concurrent with a conceptual shift to a …

Despite major advances in research into and treatment of cancer, there remain exceptional
difficulties arising from the disease's complexity and variability. These could be eased by …

The last 10 years have seen the rise of many technologies that produce an unprecedented
amount of genome-scale data from many organisms. Although the research community has …

Cancer is a heterogeneous disease, originating in different tissues and involving a number
of distinct molecular pathways. With the growing availability of high-throughput biological …

Major advances in genome science and molecular technologies provide new opportunities
at the interface between basic biological research and medical practice. The unprecedented …

A revolution is underway in the approach to studying the genetic basis of cancer. Massive
amounts of data are now being generated via high-throughput techniques such as DNA …

Delivering personalized therapeutic options to cancer patients based on the genetic and
molecular aberrations of the tumor offers great promise to improve the outcomes of cancer …

In the past decades, an enormous amount of precious information has been collected about
molecular and genetic characteristics of cancer. This knowledge is mainly based on a …

The wealth of morphological, histological, and molecular data from human cancers available
to pathologists means that pathology is poised to become a truly quantitative systems …