It is becoming evident that holistic perspectives toward cancer are crucial in deciphering the
overwhelming complexity of tumors. Single-layer analysis of genome-wide data has greatly …

Tumours are complex biological systems. No single type of molecular approach fully
elucidates tumour behaviour, necessitating analysis at multiple levels encompassing …

Publisher Summary This chapter discusses systems-based approaches to translational
medicine. This is made possible by the convergent acceleration of several disciplines …

A systems-biology approach to complex disease (such as cancer) is now complementing
traditional experience-based approaches, which have typically been invasive and …

Bioinformatics can be loosely defined as the collection, classification, storage, and analysis
of biochemical and biological information using computers and mathematical algorithms …

Molecular databases and bioinformatics methods and tools are essential for modern cancer
research. Multilevel analyses of all the protein-coding genes, thousands of proteins, and …

Abstract Systems biology focuses on the study of interacting components of biological
systems rather than on the analysis of single genes or proteins and offers a new approach to …

This teaching monograph on systems approaches to cancer research and clinical
applications provides a unique synthesis, by world-class scientists and doctors, of …

Cancer: smoother journeys for molecular data | Nature Methods Skip to main content Thank
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