Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of biomolecular data on cancer that now …

Cancer: smoother journeys for molecular data | Nature Methods Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Our understanding of cancer complexity has been dramatically improved in the last 20
years. Perou et al.(2000) started the revolution by demonstrating that the breast cancer is not …

Modelling and simulation are indispensable for the study of biological systems as dynamical
ensembles, made up of a large number of interacting components and exhibiting complex …

The development of cost-effective technologies able to comprehensively assess DNA, RNA,
protein, and metabolites in patient tumors has fueled efforts to tailor medical care. Indeed …

The current paradigm views cancer as arising clonally from a degradation of genetic
information in single cells. A complementary perspective, originating at the dawn of modern …

The future of oncology has a name: Molecular Medicine (MM). Molecular Medicine is a new
science based on three pillars. Two of them are well known and evident in its very name …

Research on the immune system and cancer has led to the development of new medicines
that enable the former to attack cancer cells. Drugs that specifically target and destroy …

A tumor often consists of multiple cell subpopulations (clones). Current chemo-treatments
often target one clone of a tumor. Although the drug kills that clone, other clones overtake it …

Due to its complexity, cancer continues to be one of the leading causes of death worldwide.
The creation of suitable preventative practices and innovative therapies is limited by the lack …