Human cancer is a complex and heterogeneous collection of diseases that kills more than
18 million people every year worldwide. Despite advances in detection, diagnosis, and …

Combined analyses of molecular data, such as DNA copy-number alteration, mRNA and
protein expression, point to biological functions and molecular pathways being deregulated …

Forecasting future trends in observable phenomena is of great interest to many disciplines.
Methods and models that are able to predict future outcomes have a variety of applications …

Unsatisfactory progress in cancer medicine and prevention calls for new research
approaches. Research can broaden its view of cancer to include not only specific molecular …

Notwithstanding decades of scientific and clinical investigation, cancer remains a disease
that endangers many lives and brings deep sorrow to many families. So far, the war on …

This volume presents an overview of recent developments in systems biology and their
applications in cancer-related research. The ongoing advances in our understanding of …

This chapter is aimed at a wide audience ranging from biologists to medical students and
cancer specialists. It provides a comprehensive overview of systems approaches to the …

Cancer Cell dedicates this special issue to. not (exclusively) the cancer cell. While
understanding maligant cells will always be our foundation and guiding principle, we …

Cancer is a disease of altered signaling and metabolism, causing uncontrolled division and
survival of transformed cells. A host of molecules, factors, and conditions have been …

This exciting SpringerBrief presents evidence for new ideas that will challenge several
theories of how cancer biology is understood. Cancer biology has undergone several …