Microglia-mediated neuroinflammation plays a crucial role in the pathophysiological process
of multiple neurological disorders such as ischemic stroke, yet lacks effective therapeutic …

Purpose Neuroinflammation plays a crucial role in neurodegenerative diseases. Matrix
metalloproteinases (MMPs) are a landmark of neuroinflammation. Lipopolysaccharide (LPS) …

Alzheimer's disease (AD) is the most common form of dementia characterized by
progressive loss of cognitive functions due to neuronal death mainly in the hippocampal and …

Background Inflammation has been found to be associated with many neurodegenerative
diseases, including Parkinson's and dementia. Attenuation of microglia-induced …

Microglia respond to adverse stimuli in order to restore brain homeostasis and, upon
activation, they release a number of inflammatory mediators. Chronic microglial …

Neuroinflammation is closely related with the pathogenesis and progress of
neurodegenerative diseases including Alzheimer's disease (AD). Loganin, an iridoid …

Oxyresveratrol (OXY), a major phytochemical component derived from several plants, has
been proved to have several pharmacological properties. However, the role of OXY in …

Alzheimer's disease (AD) is the most common form of dementia among several
neurodegenerative disorders afflicting the elderly. AD is characterized by the deposition of …

The acetylcholinesterase inhibitors donepezil and rivastigmine have been used as
therapeutic drugs for Alzheimer's disease (AD), but their effects on LPS-and Aβ-induced …

Neuroinflammation is a critical feature in the pathogenesis of neurodegenerative disorders
such as Alzheimer's disease (AD). Hesperetin can exert anti-inflammatory, antioxidant and …