Within the past four decades, there has been increasing concern about the participation of
children in medical research. The foundational role of informed consent in the ethics and …

Should children be excluded from medical research? Some child rights activists argue that
no child should ever be used for research, while many physicians claim that health care for …

Moral and regulatory questions surrounding the inclusion of, and appropriate protections for,
child subjects of research continue to pose important challenges to policy makers …

Despite an historic emphasis on protecting children from research risks, over the last few
decades medicine has come to recognize the need to include children in systematic efforts …

In recent decades, advances in biomedical research have helped save or lengthen the lives
of children around the world. With improved therapies, child and adolescent mortality rates …

Informed consent as a protection for research participants is central to modern research
ethics. Ramsey called informed consent" the canon of loyalty" and" a statement of fidelity" …

Pediatric participation in non-therapeutic research that poses greater than minimal risk has
been the subject of considerable thought-provoking debate in the research ethics literature …

In the developed world, biomedical and public health research during the 20th century
resulted in dramatic changes in maternal and infant mortality rates, the near eradication of …

In this edited volume, a diverse group of scholars present and discuss challenging cases in
the field of pediatric research ethics. After years of debate and controversy, fundamental …

Conducting pediatric research lacking clinical benefit to the subjects is sometimes essential
to test clinical interventions for children (Institute of Medicine [IOM] 2004; Wendler 2010) …