Is COVID-19 a new hematologic disease?

B Debuc, DM Smadja - Stem cell reviews and reports, 2021 - Springer
SARS-CoV-2 viruses are positive single-stranded RNA viruses, whose infection can be
asymptomatic or lead to the coronavirus disease 2019 (Covid-19). Covid-19 is a respiratory …

[HTML][HTML] Biomarkers of oxidative stress in erythrocytes as a function of human age

PK Maurya, P Kumar, P Chandra - World journal of methodology, 2015 - ncbi.nlm.nih.gov
Despite more than 300 theories to explain the aging process, oxidative stress theory offers
the best mechanism to explain aging and age related disorders. Several studies has shown …

Association of abnormal erythrocyte morphology with oxidative stress and inflammation in metabolic syndrome

P Gyawali, RS Richards, PT Bwititi… - Blood Cells, Molecules …, 2015 - Elsevier
In carrying out their role of free radical scavenging, erythrocytes become damaged due to
oxidation of membrane lipids and proteins. Such damage may change the morphology of …

Erythrocytes induce vascular dysfunction in COVID-19

A Mahdi, A Collado, J Tengbom, T Jiao… - Basic to Translational …, 2022 - jacc.org
Current knowledge regarding mechanisms underlying cardiovascular complications in
patients with COVID-19 is limited and urgently needed. We shed light on a previously …

[HTML][HTML] No evidence of hemoglobin damage by SARS-CoV-2 infection

AW DeMartino, JJ Rose, MB Amdahl, MR Dent… - …, 2020 - ncbi.nlm.nih.gov
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease (COVID-19)
has affected over 22 million patients worldwide as of August 2020. As the medical …

Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2

S Shahbaz, L Xu, M Osman, W Sligl, J Shields, M Joyce… - Stem cell reports, 2021 - cell.com
SARS-CoV-2 infection is associated with lower blood oxygen levels, even in patients without
hypoxia requiring hospitalization. This discordance illustrates the need for a more unifying …

Loss of mitochondrial membrane potential (ΔΨm) in leucocytes as post-COVID-19 sequelae

KJG Díaz-Resendiz, AB Benitez-Trinidad… - Journal of Leukocyte …, 2022 - academic.oup.com
The mitochondrial membrane potential (Δ Ψ m) is a parameter often used to determine
mitochondrial function; therefore, it can be used to determine the integrity and functionality of …

[HTML][HTML] Morphologic changes in circulating blood cells of COVID-19 patients

G Kaur, FNU Sandeep, O Olayinka, G Gupta - Cureus, 2021 - ncbi.nlm.nih.gov
Objective Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, many
studies have described the quantitative peripheral blood findings seen in COVID-19 …

[HTML][HTML] Human erythroid progenitors are directly infected by SARS-CoV-2: implications for emerging erythropoiesis in severe COVID-19 patients

HH Encabo, W Grey, M Garcia-Albornoz, H Wood… - Stem cell reports, 2021 - cell.com
We document here that intensive care COVID-19 patients suffer a profound decline in
hemoglobin levels but show an increase of circulating nucleated red cells, suggesting that …

Dynamics in anemia development and dysregulation of iron homeostasis in hospitalized patients with COVID-19

L Lanser, FR Burkert, R Bellmann-Weiler, A Schroll… - Metabolites, 2021 - mdpi.com
Anemia and disturbances of iron metabolism are frequently encountered in patients with
COVID-19 and associated with an adverse clinical course. We retrospectively analyzed 645 …