Profiles of microRNA networks in intestinal epithelial cells in a mouse model of colitis

J Lee, EJ Park, Y Yuki, S Ahmad, K Mizuguchi… - Scientific reports, 2015 - nature.com
Inflammatory bowel diseases (IBDs) accompany a critical loss of the frontline barrier function
that is achieved primarily by intestinal epithelial cells (IECs). Although the gene-regulation …

Global alteration of colonic microRNAome landscape associated with inflammatory bowel disease

E Boros, Z Hegedűs, Z Kellermayer, P Balogh… - Frontiers in …, 2022 - frontiersin.org
Inflammatory Bowel Disease (IBD) is characterized by chronic inflammation of the
gastrointestinal tract that associates with, among others, increased risk of colorectal cancer …

MicroRNAs determine human intestinal epithelial cell fate

G Dalmasso, HTT Nguyen, Y Yan, H Laroui… - Differentiation, 2010 - Elsevier
MicroRNAs (miRNAs) are small, non-coding RNA molecules that post-transcriptionally
regulate gene expression. Evidence has shown that miRNAs play important roles in various …

Differentially expressed miRNAs in ulcerative colitis and Crohn's disease

R Yarani, A Shojaeian, O Palasca… - Frontiers in …, 2022 - frontiersin.org
Differential microRNA (miRNA or miR) regulation is linked to the development and progress
of many diseases, including inflammatory bowel disease (IBD). It is well-established that …

The impact of microRNAs during inflammatory bowel disease: effects on the mucus layer and intercellular junctions for gut permeability

S Stiegeler, K Mercurio, MA Iancu, SC Corr - Cells, 2021 - mdpi.com
Research on inflammatory bowel disease (IBD) has produced mounting evidence for the
modulation of microRNAs (miRNAs) during pathogenesis. MiRNAs are small, non-coding …

Role of microRNA in inflammatory bowel disease: clinical evidence and the development of preclinical animal models

K Suri, JA Bubier, MV Wiles, LD Shultz, MM Amiji… - Cells, 2021 - mdpi.com
The dysregulation of microRNA (miRNA) is implicated in cancer, inflammation,
cardiovascular disorders, drug resistance, and aging. While most researchers study …

[HTML][HTML] MicroRNA-orchestrated pathophysiologic control in gut homeostasis and inflammation

J Lee, EJ Park, H Kiyono - BMB reports, 2016 - ncbi.nlm.nih.gov
The intestine represents the largest and most elaborate immune system organ, in which
dynamic and reciprocal interplay among numerous immune and epithelial cells, commensal …

Deep dive into microRNAs in inflammatory bowel disease

J Alfaifi, A Germain, AC Heba, D Arnone… - Inflammatory Bowel …, 2023 - academic.oup.com
Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is
thought to develop in genetically predisposed individuals as a consequence of complex …

Functional implications of microRNAs in Crohn's disease revealed by integrating microRNA and messenger RNA expression profiling

O Palmieri, TM Creanza, F Bossa, T Latiano… - International journal of …, 2017 - mdpi.com
Crohn's disease (CD) is a debilitating inflammatory bowel disease (IBD) that emerges due to
the influence of genetic and environmental factors. microRNAs (miRNAs) have been …

Identification and validation of key miRNAs and a microRNA-mRNA regulatory network associated with ulcerative colitis

S Wang, L Shen, H Luo - DNA and Cell Biology, 2021 - liebertpub.com
Ulcerative colitis (UC) is a chronic, nonspecific, intestinal inflammatory disease that involves
various genes and pathways in its pathogenesis. The current study revealed the key …