Cytokine storm and the prospects for immunotherapy with COVID-19.

LH Calabrese - Cleveland Clinic journal of medicine, 2020 - europepmc.org
Knowledge about the pathobiology of SARS-CoV-2 as it interacts with immune defenses is
limited. SARS-CoV-2 is spread by droplets that come into contact with mucous membranes …

[HTML][HTML] Immunomodulation for severe COVID-19 pneumonia: the state of the art

Y Zhang, Y Chen, Z Meng - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has become a worldwide pandemic caused by the novel coronavirus named
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe cases of COVID-19 …

SARS-CoV-2 in immunocompromised individuals

S DeWolf, JC Laracy, MA Perales, M Kamboj… - Immunity, 2022 - cell.com
Immunocompromised individuals and particularly those with hematologic malignancies are
at increased risk for SARS-CoV-2-associated morbidity and mortality due to immunologic …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …

Innate and adaptive immune responses to SARS-CoV-2 in humans: relevance to acquired immunity and vaccine responses

SC Jordan - Clinical & Experimental Immunology, 2021 - academic.oup.com
The factors responsible for the spectrum of coronavirus 19 (COVID-19) disease severity and
the genesis and nature of protective immunity against COVID-19 remain elusive. Multiple …

The pathogenesis of coronavirus-19 disease

AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …

[HTML][HTML] Covid-19: perspectives on innate immune evasion

N Taefehshokr, S Taefehshokr, N Hemmat… - Frontiers in …, 2020 - frontiersin.org
The ongoing outbreak of Coronavirus disease 2019 infection achieved pandemic status on
March 11, 2020. As of September 8, 2020 it has caused over 890,000 mortalities world-wide …

[HTML][HTML] Humoral immune responses in COVID-19 patients: a window on the state of the art

G Siracusano, C Pastori, L Lopalco - Frontiers in immunology, 2020 - frontiersin.org
The novel SARS-CoV-2 is a recently emerging virus causing a human pandemic. A great
variety of symptoms associated with COVID-19 disease, ranging from mild to severe …

Immunologic features in coronavirus disease 2019: functional exhaustion of T cells and cytokine storm

S Mahmoudi, M Rezaei, N Mansouri, M Marjani… - Journal of clinical …, 2020 - Springer
To the Editor: Since the emergence of Coronavirus Disease 2019 (COVID-19) caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, the …

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …