Topical ocular conditions such as cornea transplant rejection and keratoconjunctivitis sicca
(so called dry eye disease) require therapeutic concentration of immunosuppressant onto …

The physiological protective mechanisms of the eye reduce the bioavailability of topically
administered drugs above all for those with high molecular weight and/or lipophilic …

Dexamethasone acetate (DEX) and polymyxin B sulfate (polymyxin B) were formulated as a
cationic nanoemulsion for the treatment of ophthalmic infections. As novel concept, the …

Inflammation plays a key role in dry eye disease (DED) affecting millions of people
worldwide. Non-steroidal anti-inflammatory drugs (NSAIDs) can be used topically to act on …

Topical ophthalmic delivery of active ingredients can be achieved using cationic
nanoemulsions. In the last decade, Novagali Pharma has successfully developed and …

A combination of in situ gelling systems and a loaded drug self-assembling nanomicellar
carrier was chosen in this study as a new potential Ocular Drug Delivery System (ODDS) for …

In the present study, we aimed to formulate, optimize, and characterize azithromycin
chitosan coated niosomes (AZM-CTS-NSM) as a novel colloidal system that increases …

An ophthalmic cyclosporine (CsA) formulation based on Lipid nanocapsules (LNC) was
developed for dry eye management, aiming to provide targeting to ocular tissues with long …

The eye is the specialized part of the body and is comprised of numerous physiological
ocular barriers that limit the drug absorption at the action site. Regardless of various efforts …

Objective: The main goal of the present work was to develop and evaluate nanoemulsions
(NEs) containing acyclovir (ACV) for ophthalmic drug delivery. Method: Firstly, component …