SH Sun, Q Chen, HJ Gu, G Yang, YX Wang… - Cell host & …, 2020 - cell.com
Since December 2019, a novel coronavirus SARS-CoV-2 has emerged and rapidly spread throughout the world, resulting in a global public health emergency. The lack of vaccine and …
W Dong, H Mead, L Tian, JG Park, JI Garcia… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT A comprehensive analysis and characterization of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection model that mimics non-severe and severe …
The development of mouse models for coronavirus disease 2019 (COVID-19) has enabled testing of vaccines and therapeutics and defining aspects of severe acute respiratory …
RD Jiang, MQ Liu, Y Chen, C Shan, YW Zhou… - Cell, 2020 - cell.com
COVID-19 has spread worldwide since 2019 and is now a severe threat to public health. We previously identified the causative agent as a novel SARS-related coronavirus (SARS-CoV …
FS Oladunni, JG Park, PA Pino, O Gonzalez… - Nature …, 2020 - nature.com
Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease would benefit from validated small animal models. Here, we show that transgenic mice …
CK Yinda, JR Port, T Bushmaker, I Offei Owusu… - PLoS …, 2021 - journals.plos.org
SARS-CoV-2 emerged in late 2019 and resulted in the ongoing COVID-19 pandemic. Several animal models have been rapidly developed that recapitulate the asymptomatic to …
K Han, RV Blair, N Iwanaga, F Liu… - American journal of …, 2021 - atsjournals.org
Preclinical mouse models that recapitulate some characteristics of coronavirus disease (COVID-19) will facilitate focused study of pathogenesis and virus–host responses. Human …
Murine models of SARS-CoV-2 infection are critical for elucidating the biological pathways underlying COVID-19. Because human angiotensin-converting enzyme 2 (ACE2) is the …
C Lutz, L Maher, C Lee, W Kang - Human Genomics, 2020 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a declared pandemic that is spreading all over the world at a dreadfully fast rate. Severe acute respiratory syndrome coronavirus-2 …