Combating devastating COVID-19 by drug repurposing

AY Pawar - International Journal of Antimicrobial Agents, 2020 - Elsevier
Despite advances in drug discovery, viral infections remain a major challenge for scientists
across the globe. The recent pandemic of COVID-19 (coronavirus disease 2019), caused by …

Utilizing drug repurposing against COVID-19–efficacy, limitations, and challenges

V Parvathaneni, V Gupta - Life sciences, 2020 - Elsevier
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …

[HTML][HTML] Challenges for drug repurposing in the COVID-19 pandemic era

J Sultana, S Crisafulli, F Gabbay, E Lynn… - Frontiers in …, 2020 - frontiersin.org
The coronavirus disease (COVID-19) pandemic has affected an estimated 16 million
persons and caused 0.6 million deaths worldwide by September 2020. The pandemic has …

[PDF][PDF] Repurposing drugs for COVID-19: an approach for treatment in the pandemic

S Khadka, A Yuchi, DB Shrestha… - Altern Ther Health …, 2020 - researchgate.net
Context• Drug repurposing is a relevant approach during the COVID-19 pandemic, because
development of new drugs is time-consuming and costly, and the safety of new drugs is …

[HTML][HTML] An update on antiviral therapy against SARS-CoV-2: how far have we come?

O Indari, S Jakhmola, E Manivannan… - Frontiers in …, 2021 - frontiersin.org
COVID-19 pandemic has spread worldwide at an exponential rate affecting millions of
people instantaneously. Currently, various drugs are under investigation to treat an …

[HTML][HTML] Drug repurposing approach to fight COVID-19

TU Singh, S Parida, MC Lingaraju, M Kesavan… - Pharmacological …, 2020 - Springer
Currently, there are no treatment options available for the deadly contagious disease,
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …

COVID-19 and therapeutic drugs repurposing in hand: the need for collaborative efforts

Z Khan, Y Karataş, AF Ceylan, H Rahman - Le Pharmacien Hospitalier et …, 2021 - Elsevier
The novel pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible to cause coronavirus disease-2019 (COVID-19). It is a global pandemic disease …

Efficacy of repurposed antiviral drugs: lessons from COVID-19

MA Martinez - Drug Discovery Today, 2022 - Elsevier
The clinical, social, and economic impacts of the coronavirus disease 2019 (COVID-19)
pandemic, originated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Drug repurposing for COVID-19: A review and a novel strategy to identify new targets and potential drug candidates

L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …

Drug repurposing strategies and key challenges for COVID-19 management

S Mule, A Singh, K Greish, A Sahebkar… - Journal of Drug …, 2022 - Taylor & Francis
COVID-19 is a clinical outcome of viral infection emerged due to strain of beta coronavirus
which attacks the type-2 pneumocytes in alveoli via angiotensin-converting enzyme 2 …