[HTML][HTML] SARS-CoV-2 spike protein disrupts blood–brain barrier integrity via RhoA activation
The SARS-CoV-2 spike protein has been shown to disrupt blood–brain barrier (BBB)
function, but its pathogenic mechanism of action is unknown. Whether angiotensin …
function, but its pathogenic mechanism of action is unknown. Whether angiotensin …
[PDF][PDF] An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
Antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein
prevent SARS-CoV-2 infection. However, the effects of antibodies against other spike …
prevent SARS-CoV-2 infection. However, the effects of antibodies against other spike …
Persistent circulation of soluble and extracellular vesicle‐linked Spike protein in individuals with postacute sequelae of COVID‐19
V Craddock, A Mahajan, L Spikes… - Journal of Medical …, 2023 - Wiley Online Library
ABSTRACT SARS‐CoV‐2, the causative agent of COVID‐19 disease, has resulted in the
death of millions worldwide since the beginning of the pandemic in December 2019. While …
death of millions worldwide since the beginning of the pandemic in December 2019. While …
[HTML][HTML] Long-term effects of SARS-CoV-2 infection on human brain and memory
Q Ding, HJ Zhao - Cell Death Discovery, 2023 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have caused
several waves of outbreaks. From the ancestral strain to Omicron variant, SARS-CoV-2 has …
several waves of outbreaks. From the ancestral strain to Omicron variant, SARS-CoV-2 has …
[HTML][HTML] Cytokine signature induced by SARS-CoV-2 spike protein in a mouse model
Although COVID-19 has become a major challenge to global health, there are currently no
efficacious agents for effective treatment. Cytokine storm syndrome (CSS) can lead to acute …
efficacious agents for effective treatment. Cytokine storm syndrome (CSS) can lead to acute …
[HTML][HTML] SARS-CoV-2 spike protein: a key target for eliciting persistent neutralizing antibodies
Y Yang, L Du - Signal transduction and targeted therapy, 2021 - nature.com
A recent paper published in Science describes the detection of IgG antibody responses in
individuals infected by severe acute respiratory syndrome coronavirus (SARS-CoV-2). The …
individuals infected by severe acute respiratory syndrome coronavirus (SARS-CoV-2). The …
The neurobiology of SARS-CoV-2 infection
J Meinhardt, S Streit, C Dittmayer, RV Manitius… - Nature Reviews …, 2024 - nature.com
Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated
55–60% of those infected developing COVID-19. Since the beginning of the pandemic in …
55–60% of those infected developing COVID-19. Since the beginning of the pandemic in …
A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
X Chi, R Yan, J Zhang, G Zhang, Y Zhang, M Hao… - Science, 2020 - science.org
Developing therapeutics against severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) could be guided by the distribution of epitopes, not only on the receptor binding …
CoV-2) could be guided by the distribution of epitopes, not only on the receptor binding …
[HTML][HTML] Infectivity of SARS-CoV-2: there is something more than D614G?
SR Kannan, AN Spratt, TP Quinn, X Heng… - Journal of Neuroimmune …, 2020 - Springer
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), causative agent of
Coronavirus Disease 19 (COVID-19), has spread throughout the world since its first …
Coronavirus Disease 19 (COVID-19), has spread throughout the world since its first …
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
The recent outbreak of the betacoronavirus SARS-CoV-2 has become a significant concern
to public health care worldwide. As of August 19, 2020, more than 22,140,472 people are …
to public health care worldwide. As of August 19, 2020, more than 22,140,472 people are …