The advent of the cytokine storm

IA Clark - Immunology and cell biology, 2007 - search.proquest.com
The term 'cytokine storm'is now used in popular culture as an explanation for the distinctly
unpleasant feeling we all sense at the onset of flu. The expression certainly has common …

Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation …

O Halyabar, MH Chang, ML Schoettler… - Pediatric …, 2019 - Springer
Background Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation
syndrome (MAS) were historically thought to be distinct entities, often managed in isolation …

Cytokine release syndrome in the immunotherapy of hematological malignancies: The biology behind and possible clinical consequences

THA Tvedt, AK Vo, Ø Bruserud, H Reikvam - Journal of Clinical Medicine, 2021 - mdpi.com
Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome
characterized by fever and multiple organ dysfunction associated with (i) chimeric antigen …

Signaling pathways in the regulation of cytokine release syndrome in human diseases and intervention therapy

X Li, M Shao, X Zeng, P Qian, H Huang - Signal Transduction and …, 2021 - nature.com
Cytokine release syndrome (CRS) embodies a mixture of clinical manifestations, including
elevated circulating cytokine levels, acute systemic inflammatory symptoms and secondary …

Management of cytokine release syndrome: an update on emerging antigen-specific T cell engaging immunotherapies

RH Khadka, R Sakemura, SS Kenderian… - …, 2019 - Future Medicine
Antigen-specific immunotherapies have immense potential to harness and fortify the
inherent antitumor capacity of the immune system. Due to their unparalleled success in …

Macrophage activation syndrome in rheumatic disease: what is the role of the antigen presenting cell?

EM Behrens - Autoimmunity reviews, 2008 - Elsevier
Macrophage Activation Syndrome (MAS), alternatively referred to as secondary
hemophagocytic lymphohistiocytosis (HLH), is a complication of many rheumatic diseases …

Experience with hemophagocytic lymphohistiocytosis/macrophage activation syndrome at a single institution

AA Gupta, P Tyrrell, R Valani, S Benseler… - Journal of pediatric …, 2009 - journals.lww.com
Background Hemophagocytic lymphohistiocytosis/macrophage activation syndrome
(HLH/MAS) is a serious and potentially life threatening histiocytic disorder in children and …

The use of anakinra in the treatment of secondary hemophagocytic lymphohistiocytosis

S Bami, A Vagrecha, D Soberman… - Pediatric blood & …, 2020 - Wiley Online Library
Background Hemophagocytic lymphohistiocytosis (HLH) can be familial or secondary, which
is often triggered by infection or malignancy. HLH therapy includes dexamethasone and …