Background. Viral infections are major complications after allogeneic hematopoietic stem
cell transplantation (HSCT). During posttransplant immunosuppression the regular T-cell …

Importance of the field: Hematopoietic stem cell transplantation (HSCT) is the treatment of
choice for many hematological malignancies and genetic disorders. The majority of patients …

Viral infections remain a major cause of morbidity in patients with immunodeficiency, such
as recipients of hemopoietic stem cell transplantation. Adoptive transfer of donor-derived …

Adoptive immunotherapy—in particular, T-cell therapy—has recently emerged as a useful
strategy with the potential to overcome many of the limitations of antiviral drugs for the …

Adverse outcomes following virus-associated disease in patients receiving allogeneic
haematopoietic stem cell transplantation (HSCT) have encouraged strategies to control viral …

Despite recent advances in the field of allogeneic hematopoietic stem cell transplantation
(HSCT), viral infections are still a major complication during the period of immune …

Adoptive immunotherapy with transplant donor-derived virus-specific T cells has emerged
as a potentially curative approach for the treatment of drug-refractory EBV+ lymphomas as …

Background The adoptive transfer of allogeneic antiviral T lymphocytes derived from
seropositive donors can safely and effectively reduce or prevent the clinical manifestation of …

Donor-derived adoptive T-cell therapy is a safe and effective treatment of viral infection
posttransplant, but it is limited by donor serostatus and availability and by its personalized …

The success or failure of allogeneic stem cell transplantation (SCT) in curing a variety of
hematological disorders, centers to a large extent on the quality of the immune recovery of …