Background: Alterations in DNA methylation are stable epigenetic events that can serve as clinical biomarkers. The aim of this study was to analyze methylation patterns among various …
Background: The differential diagnosis of thyroid nodules using fine-needle aspiration biopsy (FNAB) is challenging due to the inherent limitation of the cytology tests. The use of …
JL Park, S Jeon, EH Seo, DH Bae, YM Jeong, Y Kim… - Thyroid, 2020 - liebertpub.com
Background: There are no reliable biomarkers to accurately differentiate indolent thyroid tumors from more aggressive thyroid cancers. This study aimed to develop new DNA …
L Lv, L Cao, G Hu, Q Shen, J Wu - Frontiers in genetics, 2020 - frontiersin.org
Background Aberrant DNA methylation plays an crucial role in tumorigenesis through regulating gene expression. Nevertheless, the exact role of methylation in the …
JK Stephen, KM Chen, J Merritt, D Chitale… - Journal of …, 2018 - Springer
Purpose The incidence of thyroid cancer (TC) is increasing. Cytology by itself cannot distinguish TC from some benign nodules especially in certain subtypes of TC. Our …
V Mancikova, R Buj, E Castelblanco… - … Journal of cancer, 2014 - Wiley Online Library
Thyroid cancer is a heterogeneous disease with several subtypes characterized by cytological, histological and genetic alterations, but the involvement of epigenetics is not …
RJ Ellis, Y Wang, HS Stevenson… - The Journal of …, 2014 - academic.oup.com
Context: Aberrant DNA methylation is known to be a major factor in oncogenesis and cancer progression, but effects of methylation in papillary thyroid cancer (PTC) are not well defined …
S Rodríguez-Rodero, AF Fernández… - The Journal of …, 2013 - academic.oup.com
Objective: The purpose of this study was to determine the global patterns of aberrant DNA methylation in thyroid cancer. Research Design and Methods: We have used DNA …
Background Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a recent increase in incidence in many countries. Although PTC has been explored by gene …