Context Even though the majority of well-differentiated thyroid carcinoma (WDTC) is
indolent, a number of cases display an aggressive behavior. Cumulative evidence suggests …

Background: Alterations in DNA methylation are stable epigenetic events that can serve as
clinical biomarkers. The aim of this study was to analyze methylation patterns among various …

Background: The differential diagnosis of thyroid nodules using fine-needle aspiration
biopsy (FNAB) is challenging due to the inherent limitation of the cytology tests. The use of …

Background: There are no reliable biomarkers to accurately differentiate indolent thyroid
tumors from more aggressive thyroid cancers. This study aimed to develop new DNA …

Background Aberrant DNA methylation plays an crucial role in tumorigenesis through
regulating gene expression. Nevertheless, the exact role of methylation in the …

Purpose The incidence of thyroid cancer (TC) is increasing. Cytology by itself cannot
distinguish TC from some benign nodules especially in certain subtypes of TC. Our …

Thyroid cancer is a heterogeneous disease with several subtypes characterized by
cytological, histological and genetic alterations, but the involvement of epigenetics is not …

Context: Aberrant DNA methylation is known to be a major factor in oncogenesis and cancer
progression, but effects of methylation in papillary thyroid cancer (PTC) are not well defined …

Objective: The purpose of this study was to determine the global patterns of aberrant DNA
methylation in thyroid cancer. Research Design and Methods: We have used DNA …

Background Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a
recent increase in incidence in many countries. Although PTC has been explored by gene …