The nucleolus is a dynamic structure that has roles in various physiological and
pathophysiological processes. Perturbations on many aspects of the nucleolar functions are …

The nucleolus is a prominent subnuclear compartment, where ribosome biosynthesis takes
place. Recently, the nucleolus has gained attention for its novel role in the regulation of …

The nucleolus is the site of ribosome biogenesis and is found to play an important role in
stress sensing. For over 100 years, the increase in the size and number of nucleoli has been …

All organisms sense and respond to conditions that stress their homeostaticmechanisms.
Here we review current studies showing that the nucleolus, long regardedas a mere …

The nucleolus is a highly dynamic nuclear substructure that was originally described as the
site of ribosome biogenesis. The advent of proteomic analysis has now allowed the …

The nucleolus is a large nuclear membraneless organelle responsible for ribosome
biogenesis. Ribosomes are cytoplasmic macromolecular complexes comprising RNA and …

The nucleolus is a stress sensor and compromised nucleolar activity may be considered as
an attractive anticancer strategy. In the present study, the effects of three plant-derived …

The contribution of the nucleolus to cancer is well established with respect to its traditional
role in facilitating ribosome biogenesis and proliferative capacity. More contemporary …

Ribosome biogenesis in the nucleolus is an important process that consumes 80% of a cell's
intracellular energy supply. Disruption of this process results in nucleolar stress, triggering …

Besides the canonical function in ribosome biogenesis, there have been significant recent
advances towards the fascinating roles of the nucleolus in stress response, cell destiny …