Histone acetylation and methylation: combinatorial players for transcriptional regulation
W An - Chromatin and Disease, 2007 - Springer
Post-synthetic modification of histone proteins in chromatin architecture plays a central role
in the epigenetic regulation of transcription. Histone acetylation and methylation are the two …
in the epigenetic regulation of transcription. Histone acetylation and methylation are the two …
Simple histone acetylation plays a complex role in the regulation of gene expression
H Fukuda, N Sano, S Muto… - Briefings in Functional …, 2006 - academic.oup.com
Eukaryotic DNA is packaged into chromatin by histone proteins, which assemble the DNA
into an organized, higher-order structure. The precise organization of chromatin is essential …
into an organized, higher-order structure. The precise organization of chromatin is essential …
Linking histone acetylation to transcriptional regulation
CA Mizzen, CD Allis - Cellular and molecular life sciences CMLS, 1998 - Springer
In eukaryotes, DNA is assembled with histones to form nucleosomes, the basic subunit of
chromatin structure. The wrapping of DNA around histone octamers to form nucleosomal …
chromatin structure. The wrapping of DNA around histone octamers to form nucleosomal …
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
Y Zhang, D Reinberg - Genes & development, 2001 - genesdev.cshlp.org
In this review, we discuss recent advances made on histone methylation and its diverse
functions in regulating gene expression. Methylation of histone polypeptides might be static …
functions in regulating gene expression. Methylation of histone polypeptides might be static …
[PDF][PDF] Histone modifications as key regulators of transcription
AU Khan, S Krishnamurthy - Front Biosci, 2005 - Citeseer
[Frontiers in Bioscience 10, 866-872, January 1, 2005] 866 HISTONE MODIFICATIONS AS KEY
REGULATORS OF TRANSCRIPTION Asad U Khan Page 1 [Frontiers in Bioscience 10, 866-872 …
REGULATORS OF TRANSCRIPTION Asad U Khan Page 1 [Frontiers in Bioscience 10, 866-872 …
[引用][C] A SAGA of histone acetylation and gene expression
M Hampsey - Trends in Genetics, 1997 - Elsevier
A fundamental question in molecular biology is how the transcriptional machinery cont., Ms
with the chromatin structure of eukaryotic DNA to activate gene expression. Histone …
with the chromatin structure of eukaryotic DNA to activate gene expression. Histone …
Covalent modifications of histones: expression from chromatin templates
JR Davie - Current opinion in genetics & development, 1998 - Elsevier
Recent advances highlight the involvement of histone acetyltransferases in transcriptional
activation and histone deacetylases in transcriptional repression. Transcription factors …
activation and histone deacetylases in transcriptional repression. Transcription factors …
Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation
JE Brownell, CD Allis - Current opinion in genetics & development, 1996 - Elsevier
Post-translational acetylation of the core histone amino-terminal tails has long been
associated with both chromatin assembly and the regulation of gene expression. The recent …
associated with both chromatin assembly and the regulation of gene expression. The recent …
HATs on and beyond chromatin
The role of histone acetylation as a key mechanism of transcriptional regulation has been
well established. Recent advances suggest that histone acetyltransferases also play …
well established. Recent advances suggest that histone acetyltransferases also play …
Lessons from genome-wide studies: an integrated definition of the coactivator function of histone acetyl transferases
Histone acetylation is one of the key regulatory mechanisms controlling transcriptional
activity in eukaryotic cells. In higher eukaryotes, a number of nuclear histone …
activity in eukaryotic cells. In higher eukaryotes, a number of nuclear histone …