A key question in understanding the functional role of lipid rafts is whether lipid
microdomains at the plasma membrane outer leaflet are coupled to lipid microdomains at …

During the past decade, the lipid‐raft hypothesis has focused attention on the role of
membrane domains in controlling cellular functions. Among the best‐studied roles of lipid …

There is now considerable evidence suggesting that the plasma membrane of mammalian
cells is compartmentalized by functional lipid raft microdomains. These structures are …

Lipid rafts are defined as detergent-resistant membrane microdomains of specific lipid and
protein composition. They are involved in many aspects of cell biology, including T-cell …

Lipid rafts are important signaling platforms in T cells. Little is known about their properties in
human CD8+ T cells. We studied polarization of lipid rafts by digital immunofluorescence …

Copyright 2000 Academic PressPlasma membranes of many cell types contain domains
enriched in specific lipids and cholesterol, called lipid rafts. In T lymphocytes, key T cell …

Physically distinct cholesterol/sphingolipid-rich plasma membrane microdomains, so-called
lipid rafts, have been recognized to play an important regulatory role in various cellular …

Accumulating evidence strongly supports the role of lipid rafts in the regulation of T‐
lymphocyte activation, but the organization and molecular composition of these cholesterol …

The existence of lipid rafts and their importance for immunoreceptor signaling is highly
debated. By non-invasive single molecule imaging, we analyzed the dynamics of the T-cell …

Experimental evidence indicates that the mammalian cell membrane is compartmentalized.
A structural feature that supports membrane segmentation implicates assemblies of selected …