Brain dopamine receptors have been preferred targets for numerous pharmacological
compounds developed for the treatment of various neuropsychiatric disorders. Recent …

Drugs that act on dopamine neurotransmission are important tools for the management of
multiple neuropsychiatric disorders. Classically, dopamine receptors have been shown to …

Psychotropic drugs acting on monoamine neurotransmission are major pharmacological
treatments for neuropsychiatric conditions such as schizophrenia, depression, bipolar …

Dopamine plays important roles in normal brain function and many neuropsychiatric
disorders. Classically, dopamine receptors are positively coupled to G protein-mediated …

Mental illnesses, such as bipolar disorder, attention-deficit/hyperactivity disorder, depression
and schizophrenia are a major public health concern worldwide. Several pharmacologic …

Several studies in rodent models have shown that glycogen synthase kinase 3 β (GSK3β)
plays an important role in the actions of antispychotics and mood stabilizers. Recently it was …

The serine/threonine kinase Akt is a downstream target of dopamine receptor signaling that
is inhibited/dephosphorylated in response to direct and indirect dopamine receptor agonists …

Despite their distinct targets, all addictive drugs commonly abused by humans evoke
increases in dopamine (DA) concentration within the striatum. The main DA Guanine …

Dopamine plays an important role in the etiology of schizophrenia, and D2 class dopamine
receptors are the best-established target of antipsychotic drugs. Here we show that D2 class …

Drug addiction represents a pathological form of neuroplasticity along with the emergence of
aberrant behaviors involving a cascade of neurochemical changes mainly in the brain's …