Genetic drivers of m6A methylation in human brain, lung, heart and muscle
The most prevalent post-transcriptional mRNA modification, N 6-methyladenosine (m6A),
plays diverse RNA-regulatory roles, but its genetic control in human tissues remains …
plays diverse RNA-regulatory roles, but its genetic control in human tissues remains …
The RNA N6-methyladenosine modification landscape of human fetal tissues
S Xiao, S Cao, Q Huang, L Xia, M Deng, M Yang… - Nature cell …, 2019 - nature.com
A single genome gives rise to diverse tissues through complex epigenomic mechanisms,
including N 6-methyladenosine (m6A), a widespread RNA modification that is implicated in …
including N 6-methyladenosine (m6A), a widespread RNA modification that is implicated in …
m6A-TSHub: Unveiling the Context-Specific m6A Methylation and m6A-Affecting Mutations in 23 Human Tissues
As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …
Comprehensive analysis of mRNA methylation reveals enrichment in 3′ UTRs and near stop codons
Methylation of the N 6 position of adenosine (m 6 A) is a posttranscriptional modification of
RNA with poorly understood prevalence and physiological relevance. The recent discovery …
RNA with poorly understood prevalence and physiological relevance. The recent discovery …
[HTML][HTML] scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
Summary N 6-methyladenosine (m 6 A) is an abundant RNA modification that plays critical
roles in RNA regulation and cellular function. Global m 6 A profiling has revealed important …
roles in RNA regulation and cellular function. Global m 6 A profiling has revealed important …
Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability
Abstract N 6-methyladenosine (m6A) plays important roles in regulating messenger RNA
processing. Despite rapid progress in this field, little is known about the genetic …
processing. Despite rapid progress in this field, little is known about the genetic …
Landscape and regulation of m6A and m6Am methylome across human and mouse tissues
Summary N 6-methyladenosine (m 6 A), the most abundant internal mRNA modification, and
N 6, 2′-O-dimethyladenosine (m 6 Am), found at the first-transcribed nucleotide, are two …
N 6, 2′-O-dimethyladenosine (m 6 Am), found at the first-transcribed nucleotide, are two …
Exon architecture controls mRNA m6A suppression and gene expression
N 6-methyladenosine (m6A) is the most abundant messenger RNA (mRNA) modification
and plays crucial roles in diverse physiological processes. Using a massively parallel assay …
and plays crucial roles in diverse physiological processes. Using a massively parallel assay …
N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer's disease
Abstract Background N6-methyladenosine (m 6 A) modification is known to impact many
aspects of RNA metabolism, including mRNA stability and translation, and is highly …
aspects of RNA metabolism, including mRNA stability and translation, and is highly …
Region-specific RNA m6A methylation represents a new layer of control in the gene regulatory network in the mouse brain
M Chang, H Lv, W Zhang, C Ma, X He… - Open …, 2017 - royalsocietypublishing.org
N6-methyladenosine (m6A) is the most abundant epitranscriptomic mark found on mRNA
and has important roles in various physiological processes. Despite the relatively high m6A …
and has important roles in various physiological processes. Despite the relatively high m6A …