Infection of human lymphomononuclear cells by SARS-CoV-2

MC Pontelli, IA Castro, RB Martins, FP Veras… - BioRxiv, 2020 - biorxiv.org
Although SARS-CoV-2 severe infection is associated with a hyperinflammatory state,
lymphopenia is an immunological hallmark, and correlates with poor prognosis in COVID …

[HTML][HTML] T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19

F Venet, M Gossez, F Bidar, M Bodinier… - …, 2022 - thelancet.com
Background In critically ill COVID-19 patients, the initial response to SARS-CoV-2 infection
is characterized by major immune dysfunctions. The capacity of these severe patients to …

[PDF][PDF] Alterations in lymphocyte subsets and monocytes in patients diagnosed with SARS-CoV-2 pneumonia: a mini review of the literature.

M Lagadinou, N Zareifopoulos… - European Review for …, 2021 - europeanreview.org
OBJECTIVE: Complete blood count parameters are frequently altered in COVID-19 patients.
Leucopenia and lymphopenia are the most common findings. This is not specific to COVID …

Clinical and laboratory profiles of 75 hospitalized patients with novel coronavirus disease 2019 in Hefei, China

Z Zhao, J Xie, M Yin, Y Yang, H He, T Jin, W Li, X Zhu… - MedRxiv, 2020 - medrxiv.org
The outbreak of the novel coronavirus disease 2019 (COVID-19) infection began in
December 2019 in Wuhan, and rapidly spread to many provinces in China. The number of …

COVID-19 pneumonia: CD8+ T and NK cells are decreased in number but compensatory increased in cytotoxic potential

Y Jiang, X Wei, J Guan, S Qin, Z Wang, H Lu, J Qian… - Clinical …, 2020 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19) is posing a huge threat to
human health worldwide. We aim to investigate the immune status of CD8+ T and NK cells …

[HTML][HTML] Severe COVID-19 is characterized by the co-occurrence of moderate cytokine inflammation and severe monocyte dysregulation

B Bonnet, J Cosme, C Dupuis, E Coupez, M Adda… - …, 2021 - thelancet.com
Background SARS-CoV-2 has been responsible for considerable mortality worldwide, owing
in particular to pulmonary failures such as ARDS, but also to other visceral failures and …

[HTML][HTML] The immune, inflammatory and hematological response in COVID-19 patients, according to the severity of the disease

F Trofin, EV Nastase, A Vâță, LS Iancu, C Luncă… - Microorganisms, 2023 - mdpi.com
Introduction: The aim of this study was to evaluate the immune and inflammatory responses
in COVID-19 patients by dosing specific IgM and IgG total antibodies and interleukin 6 …

[HTML][HTML] Longitudinal cytokine profile in patients with mild to critical COVID-19

L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …

Higher level of neutrophil-to-lymphocyte is associated with severe COVID-19

M Kong, H Zhang, X Cao, X Mao, Z Lu - Epidemiology & Infection, 2020 - cambridge.org
In December 2019, cases of severe coronavirus 2019 (COVID-19) infection rapidly
progressed to acute respiratory failure. This study aims to assess the association between …

Lymphocyte subsets early predict mortality in a large series of hospitalized COVID-19 patients in Spain

S Cantenys-Molina, E Fernández-Cruz… - Clinical & …, 2021 - academic.oup.com
The role of lymphocytes and their main subsets as prognostic factors of death in SARS-CoV-
2-infected patients remains unclear, with no information obtained from patients outside …