Fibroblasts and macrophages are universal cell types across all mammalian tissues. These
cells differ in many ways including their cellular origins; dynamics of renewal, recruitment …

Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …

During development and throughout adult life, macrophages derived from hematopoietic
progenitors are seeded throughout the body, initially in the absence of inflammatory and …

One of the most important but as yet unanswered questions in inflammation research is not
why inflammation occurs (we all get episodes of self limiting inflammation during the course …

Fibroblasts are known for their ability to make and modify the extracellular matrix. However,
there is more to them than meets the eye. It is now clear that they help define tissue …

Macrophages, and more broadly inflammation, have been considered for a long time as bad
markers of tissue homeostasis. However, if it is indisputable that macrophages are …

Macrophages form a heterogeneous group of hematopoietic cells that reside in tissues,
where they are required to maintain organ integrity. Tissue macrophages contribute to tissue …

The understanding of macrophages and their pathophysiological role has dramatically
changed within the last decades. Macrophages represent a very interesting cell type with …

Fibrocytes are mesenchymal cells that arise from monocyte precursors. They are present in
injured organs and have both the inflammatory features of macrophages and the tissue …

Macrophages are versatile cells of the hematopoietic system that display remarkable
functional diversity encompassing innate immune responses, tissue development, and …