Fluorogenic hybridization probes that allow RNA imaging provide information as to how the
synthesis and transport of particular RNA molecules is orchestrated in living cells. In this …

In light of the increasing importance assigned to RNA, significant efforts have been devoted
to the development of fluorescent oligonucleotide probes that allow the imaging of RNA …

We have developed a new class of triplex-forming peptide nucleic acid (PNA)-based
fluorogenic probes for sensing of the panhandle structure of the influenza A virus (IAV) RNA …

Live cell imaging of mRNA-protein interactions makes it possible to study posttranscriptional
processes of cellular and viral gene expression under physiological conditions. In this study …

GFP-like fluorescent proteins and their molecular mimics have revolutionized bioimaging
research, but their emissions are largely limited in the visible to far-red region, hampering …

Seasonal influenza A viruses cause annual epidemics of respiratory disease; highly
pathogenic avian H5N1 and the recently emerged H7N9 viruses cause severe infections in …

The simultaneous imaging of different RNA molecules in homogeneous solution is a
challenge and requires optimisation to enable unambiguous staining of intracellular RNA …

Real-time fluorescence imaging of viral proteins in living cells provides a valuable means to
study virus-host interactions. The challenge of generating replication-competent fluorescent …

Efficient fluorogenic hybridization probes combine high brightness and specificity of
fluorescence signaling with large turn-on of fluorescence. Herein, we present an approach …

Oligonucleotide probes that show enhanced fluorescence upon nucleic acid hybridization
enable the detection and visualization of specific mRNA molecules, in vitro and in cellulo. A …