SAveRUNNER: A network-based algorithm for drug repurposing and its application to COVID-19

G Fiscon, F Conte, L Farina, P Paci - PLoS computational biology, 2021 - journals.plos.org
The novelty of new human coronavirus COVID-19/SARS-CoV-2 and the lack of effective
drugs and vaccines gave rise to a wide variety of strategies employed to fight this worldwide …

SAveRUNNER: an R-based tool for drug repurposing

G Fiscon, P Paci - BMC bioinformatics, 2021 - Springer
Background Currently, no proven effective drugs for the novel coronavirus disease COVID-
19 exist and despite widespread vaccination campaigns, we are far short from herd …

[HTML][HTML] Network bioinformatics analysis provides insight into drug repurposing for COVID-19

X Li, J Yu, Z Zhang, J Ren, AE Peluffo, W Zhang… - Medicine in Drug …, 2021 - Elsevier
The COVID-19 disease caused by the SARS-CoV-2 virus is a health crisis worldwide. While
developing novel drugs and vaccines is long, repurposing existing drugs against COVID-19 …

[HTML][HTML] In silico drug repurposing in COVID-19: A network-based analysis

P Sibilio, S Bini, G Fiscon, M Sponziello, F Conte… - Biomedicine & …, 2021 - Elsevier
The SARS-CoV-2 pandemic is a worldwide public health emergency. Despite the beginning
of a vaccination campaign, the search for new drugs to appropriately treat COVID-19 …

Machine learning and network medicine approaches for drug repositioning for COVID-19

S de Siqueira Santos, M Torres, D Galeano… - Patterns, 2022 - cell.com
We present two machine learning approaches for drug repurposing. While we have
developed them for COVID-19, they are disease-agnostic. The two methodologies are …

[HTML][HTML] A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19

F Ahmed, AM Soomro, ARC Salih… - Biomedicine & …, 2022 - Elsevier
Conventional drug discovery and development is tedious and time-taking process; because
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …

Using informative features in machine learning based method for COVID-19 drug repurposing

R Aghdam, M Habibi, G Taheri - Journal of cheminformatics, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by a novel virus named Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). This virus induced a large …

Deep learning for drug repurposing: Methods, databases, and applications

X Pan, X Lin, D Cao, X Zeng, PS Yu… - Wiley …, 2022 - Wiley Online Library
Drug development is time‐consuming and expensive. Repurposing existing drugs for new
therapies is an attractive solution that accelerates drug development at reduced …

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

Y Zhou, Y Hou, J Shen, Y Huang, W Martin, F Cheng - Cell discovery, 2020 - nature.com
Human coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus
(SARS-CoV) and 2019 novel coronavirus (2019-nCoV, also known as SARS-CoV-2), lead …

Network analytics for drug repurposing in COVID-19

N Siminea, V Popescu… - Briefings in …, 2022 - academic.oup.com
To better understand the potential of drug repurposing in COVID-19, we analyzed control
strategies over essential host factors for SARS-CoV-2 infection. We constructed …