Prediction of mortality in adult patients with sepsis using six biomarkers: a systematic review and meta-analysis
A Pregernig, M Müller, U Held… - Annals of intensive care, 2019 - Springer
Abstract Background Angiopoietin-1 (Ang-1) and 2 (Ang-2), high mobility group box 1
(HMGB1), soluble receptor for advanced glycation endproducts (sRAGE), soluble triggering …
(HMGB1), soluble receptor for advanced glycation endproducts (sRAGE), soluble triggering …
[HTML][HTML] The relationship between acuity of organ failure and predictive validity of sepsis-3 criteria
SM Gadrey, R Clay, AN Zimmet, AS Lawson… - Critical care …, 2020 - journals.lww.com
Objectives: The Sepsis-3 taskforce defined sepsis as suspicion of infection and an acute rise
in the Sequential Organ Failure Assessment score by 2 points over the preinfection …
in the Sequential Organ Failure Assessment score by 2 points over the preinfection …
Clinical and microbiological characterization of sepsis and evaluation of sepsis scores
A Fuchs, TB Tufa, J Hörner, Z Hurissa, T Nordmann… - PLoS …, 2021 - journals.plos.org
Background Despite the necessity of early recognition for an optimal outcome, sepsis often
remains unrecognized. Available tools for early recognition are rarely evaluated in low-and …
remains unrecognized. Available tools for early recognition are rarely evaluated in low-and …
Quick sequential organ failure assessment compared to systemic inflammatory response syndrome for predicting sepsis in emergency department
HK Park, WY Kim, MC Kim, W Jung, BS Ko - Journal of critical care, 2017 - Elsevier
Purpose It is unclear whether quick sequential (sepsis-related) organ failure assessment
(qSOFA) also has prognostic value for organ failure in patients with a suspected infection …
(qSOFA) also has prognostic value for organ failure in patients with a suspected infection …
Albumin corrected anion gap for predicting in-hospital mortality among intensive care patients with sepsis: a retrospective propensity score matching analysis
T Hu, Z Zhang, Y Jiang - Clinica chimica acta, 2021 - Elsevier
Background The relationship between albumin corrected anion gap (ACAG) and in-hospital
mortality of intensive care sepsis patients is currently inconclusive. Methods The baseline …
mortality of intensive care sepsis patients is currently inconclusive. Methods The baseline …
Biomarkers and clinical scores to aid the identification of disease severity and intensive care requirement following activation of an in-hospital sepsis code
J Baldirà, JC Ruiz-Rodríguez, DC Wilson… - Annals of intensive …, 2020 - Springer
Background Few validated biomarker or clinical score combinations exist which can
discriminate between cases of infection and other non-infectious conditions following …
discriminate between cases of infection and other non-infectious conditions following …
The evolution of activated protein C plasma levels in septic shock and its association with mortality: a prospective observational study
T Becher, J Müller, I Akin, S Baumann, K Bosch… - Journal of Critical …, 2018 - Elsevier
Purpose Septic shock is commonly associated with hemostatic abnormalities. The
endothelium-activated serine protease activated protein C (APC) plays a pivotal role in …
endothelium-activated serine protease activated protein C (APC) plays a pivotal role in …
The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis
Background Sepsis, the dysregulated host response to infection, triggers abnormal pro-
coagulant and pro-inflammatory host responses. Limitations in early disease intervention …
coagulant and pro-inflammatory host responses. Limitations in early disease intervention …
Diagnostic and prognostic value of presepsin vs. established biomarkers in critically ill patients with sepsis or systemic inflammatory response syndrome
H Brodska, J Valenta, K Pelinkova, Z Stach… - Clinical Chemistry and …, 2018 - degruyter.com
Background: Inflammatory biomarkers may aid to distinguish between systemic inflammatory
response syndrome (SIRS) vs. sepsis. We tested the hypotheses that (1) presepsin, a novel …
response syndrome (SIRS) vs. sepsis. We tested the hypotheses that (1) presepsin, a novel …
qSOFA combined with suPAR for early risk detection and guidance of antibiotic treatment in the emergency department: a randomized controlled trial
ME Adami, A Kotsaki, N Antonakos, E Giannitsioti… - Critical Care, 2024 - Springer
Background Sepsis guidelines suggest immediate start of resuscitation for patients with
quick Sequential Organ Failure Assessment (qSOFA) 2 or 3. However, the interpretation of …
quick Sequential Organ Failure Assessment (qSOFA) 2 or 3. However, the interpretation of …