Tris (2-butoxyethyl) phosphate (TBEP): A flame retardant in solid waste display hepatotoxic and carcinogenic risks for humans

Q Saquib, AM Al-Salem, MA Siddiqui, SM Ansari… - Chemosphere, 2022 - Elsevier
Recent reports have confirmed that tris (2-butoxyethyl) phosphate (TBEP), an
organophosphorous flame retardants (OPFRs), profoundly detected in the dust from solid …

Pterostilbene suppresses oxidative stress and allergic airway inflammation through AMPK/Sirt1 and Nrf2/HO‐1 pathways

C Xu, Y Song, Z Wang, J Jiang, Y Piao… - Immunity …, 2021 - Wiley Online Library
Abstract Introduction Pterostilbene (Pts) may be used for allergic asthma treatment. The
AMPK/Sirt1 and Nrf2/HO‐1 pathways are potential targets for asthma treatement. However …

In vitro immunotoxicity of organophosphate flame retardants in human THP-1-derived macrophages

X Li, N Li, K Rao, Q Huang, M Ma - Environmental Science & …, 2020 - ACS Publications
Scarce attention has been paid to the immunotoxicity of organophosphate flame retardants
(PFRs), which poses a challenge to the systematic assessment of their health risks. In this …

Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq

BV Krivoshiev, GTS Beemster, K Sprangers, B Cuypers… - Toxicology in vitro, 2018 - Elsevier
Abstract Tris (2-butoxyethyl) phosphate (TBOEP) is a compound produced at high volume
that is used as both a flame retardant and a plasticizer. It is persistent and bioaccumulative …

Pi-Pa-Run-Fei-Tang alleviates lung injury by modulating IL-6/JAK2/STAT3/IL-17 and PI3K/AKT/NF-κB signaling pathway and balancing Th17 and Treg in murine …

XL Jie, ZR Luo, J Yu, ZR Tong, QQ Li, JH Wu… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Pi-Pa-Run-Fei-Tang (PPRFT) is an empirical
TCM prescription for treating asthma. However, the underlying mechanisms of PPRFT in …

Uptake, Accumulation, and Biomarkers of PM2.5-Associated Organophosphate Flame Retardants in C57BL/6 Mice after Chronic Exposure at Real Environmental …

M Chen, X Liao, S Yan, Y Gao, C Yang… - Environmental …, 2020 - ACS Publications
Although the bioaccumulation of organophosphate flame retardants (OPFRs) in aquatic
organisms has been investigated, little information is available about their bioaccumulation …

Exposure to organophosphate flame retardants and plasticizers is positively associated with wheeze and FeNO and eosinophil levels among school-aged children …

Y Zeng, H Goudarzi, YA Bamai, RM Ketema… - Environment …, 2023 - Elsevier
Exposure to organophosphate flame retardants and plasticizers (PFRs) increases the risk of
asthma and allergies. However, little is known about its association with type 2 inflammation …

Lethal concentration of perfluoroisobutylene induces acute lung injury in mice mediated via cytokine storm, oxidative stress and apoptosis

Y Zhang, L Fan, R Xi, Z Mao, D Shi, D Ding… - Inhalation …, 2017 - Taylor & Francis
Perfluoroisobutylene (PFIB) is a highly toxic gas that targets the lungs. Low-level inhalation
of the gas can lead to acute lung injury (ALI), pulmonary edema and even death. No specific …

The cytotoxicity of organophosphate flame retardants on HepG2, A549 and Caco-2 cells

J An, J Hu, Y Shang, Y Zhong, X Zhang… - … Science and Health …, 2016 - Taylor & Francis
In order to elucidate the cytotoxicity of organophosphate flame retardants (OPFRs), three
human in vitro models, namely the HepG2 hepatoma cells, the A549 lung cancer cells and …

Perfluorooctanesulfonate and perfluorooctanoate exacerbate airway inflammation in asthmatic mice and in vitro

M Yang, LY Li, XD Qin, XY Ye, S Yu, Q Bao… - Science of the Total …, 2021 - Elsevier
Emerging evidence suggests associations between Perfluoroalkyl substances (PFASs)
exposure and asthma, but the findings are inconsistent. The current study sought to …