Perinatal triphenyl phosphate exposure induces metabolic dysfunctions through the EGFR/ERK/AKT signaling pathway: Mechanistic in vitro and in vivo studies

P Tachachartvanich, X Rusit, J Tong, C Mann… - Ecotoxicology and …, 2024 - Elsevier
Triphenyl phosphate (TPhP), a widely used organophosphate-flame retardant, is
ubiquitously found in household environments and may adversely affect human health …

Comparative assessment of neurotoxicity impacts induced by alkyl tri‐n‐butyl phosphate and aromatic tricresyl phosphate in PC12 cells

Y Chang, H Cui, X Jiang, M Li - Environmental toxicology, 2020 - Wiley Online Library
Organophosphate flame retardants (OPFRs) have become a growing concern due to their
potential environmental and health risk. However, limited studies have described the toxicity …

Levels of blood organophosphorus flame retardants and association with changes in human sphingolipid homeostasis

F Zhao, Y Wan, H Zhao, W Hu, D Mu… - Environmental …, 2016 - ACS Publications
While a recent toxicological study has shown that organophosphorus flame retardants
(OPFRs) may disrupt sphingolipid homeostasis, epidemiologic evidence is currently lacking …

Hippocampal proteomic analysis reveals the disturbance of synaptogenesis and neurotransmission induced by developmental exposure to organophosphate flame …

X Zhong, Y Yu, C Wang, Q Zhu, J Wu, W Ke, D Ji… - Journal of Hazardous …, 2021 - Elsevier
With the spread of organophosphorus flame retardants (OPFRs), the environmental and
health risks they induce are attracting attention. Triphenyl phosphate (TPHP) is a popular …

[HTML][HTML] Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease in mice via the Keap1/Nrf2 axis

H Song, L Jiang, W Yang, Y Dai, Y Wang, Z Li… - Biomedicine & …, 2023 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity worldwide.
Cigarette smoking, which leads to abnormalities in the airways or alveoli and persistent …

Fine particulate matter and sulfur dioxide coexposures induce rat lung pathological injury and inflammatory responses via TLR4/p38/NF-κB pathway

R Li, L Zhao, J Tong, Y Yan… - International journal of …, 2017 - journals.sagepub.com
Fine particulate matter (PM2. 5) and sulfur dioxide (SO2) are 2 common air pollutants, but
their toxicological effects of coexposure are still not fully clear. In this study, SO2 exposure …

Screening of organophosphate flame retardants with placentation-disrupting effects in human trophoblast organoid model and characterization of adverse pregnancy …

C Xu, H Ma, F Gao, C Zhang, W Hu, Y Jia… - Environmental Health …, 2022 - ehp.niehs.nih.gov
Background: Abnormal placental development may result in adverse pregnancy outcomes
and metabolic diseases in adulthood; however, it remains unknown whether and how …

[HTML][HTML] Oral exposure to low dose bisphenol A aggravates allergic airway inflammation in mice

R Yanagisawa, E Koike, TT Win-Shwe, H Takano - Toxicology Reports, 2019 - Elsevier
Bisphenol A (BPA) is widely used in many consumer products and has adverse effects on
human health including allergic diseases. We investigated the effects of low dose BPA …

Brominated flame retardants, hexabromocyclododecane and tetrabromobisphenol A, affect proinflammatory protein expression in human bronchial epithelial cells via …

E Koike, R Yanagisawa, H Takano - Toxicology In Vitro, 2016 - Elsevier
Hexabromocyclododecane (HBCD) and tetrabromobisphenol A (TBBPA) are widely used as
brominated flame retardants (BFRs) in consumer products. Because humans can be …

Effects of oral exposure to low-dose Bisphenol S on allergic asthma in mice

R Yanagisawa, E Koike, TT Win-Shwe… - International Journal of …, 2022 - mdpi.com
Bisphenol S (BPS) is increasingly being used as an alternative for bisphenol A; however, its
health effects remain unclear. We investigated the effects of oral exposure to low-dose BPS …