Benzo[a]pyrene induces NLRP1 expression and promotes prolonged inflammasome signaling

R Kohno, Y Nagata, T Ishihara, C Amma… - Frontiers in …, 2023 - frontiersin.org
Benzo [a] pyrene (BaP), a polycyclic aromatic hydrocarbon in the air, triggers pulmonary
inflammation. This study focused on BaP-induced inflammation in the alveolar epithelium …

[HTML][HTML] Oral exposure to low dose bisphenol A aggravates allergic airway inflammation in mice

R Yanagisawa, E Koike, TT Win-Shwe, H Takano - Toxicology Reports, 2019 - Elsevier
Bisphenol A (BPA) is widely used in many consumer products and has adverse effects on
human health including allergic diseases. We investigated the effects of low dose BPA …

Fine particulate matter and sulfur dioxide coexposures induce rat lung pathological injury and inflammatory responses via TLR4/p38/NF-κB pathway

R Li, L Zhao, J Tong, Y Yan… - International journal of …, 2017 - journals.sagepub.com
Fine particulate matter (PM2. 5) and sulfur dioxide (SO2) are 2 common air pollutants, but
their toxicological effects of coexposure are still not fully clear. In this study, SO2 exposure …

Presence and human exposure assessment of organophosphate flame retardants (OPEs) in indoor dust and air in Beijing, China

D Cao, K Lv, W Gao, J Fu, J Wu, J Fu, Y Wang… - Ecotoxicology and …, 2019 - Elsevier
In this study, levels of 14 organophosphate flame retardants (OPEs) were measured in 101
indoor dust samples collected from dormitories, residential homes, and offices in Beijing …

Epigallocatechin gallate potentially abrogates fluoride induced lung oxidative stress, inflammation via Nrf2/Keap1 signaling pathway in rats: An in-vivo and in-silico …

T Shanmugam, M Selvaraj, S Poomalai - International …, 2016 - Elsevier
Abstract Background Since this Nrf2-dependent cellular defense response is able to protect
multi-organs, including cancer, neurodegenerative diseases, cardiovascular diseases …

Screening of organophosphate flame retardants with placentation-disrupting effects in human trophoblast organoid model and characterization of adverse pregnancy …

C Xu, H Ma, F Gao, C Zhang, W Hu, Y Jia… - Environmental Health …, 2022 - ehp.niehs.nih.gov
Background: Abnormal placental development may result in adverse pregnancy outcomes
and metabolic diseases in adulthood; however, it remains unknown whether and how …

[HTML][HTML] NLRP12 attenuates ozone-induced pulmonary inflammation by regulating canonical NF-κB Pathway

M Li, Y Xue, X Miao, P Ma, X Kong, Y Jin, Y Li… - Ecotoxicology and …, 2023 - Elsevier
Ozone (O 3) is an important urban air pollutant having strong correlations with respiratory
diseases. Several lines of evidence suggest that O 3 exposure causes airway …

[HTML][HTML] Xuanfei Baidu formula alleviates impaired mitochondrial dynamics and activated NLRP3 inflammasome by repressing NF-κB and MAPK pathways in LPS …

Z Li, H Pan, J Yang, D Chen, Y Wang, H Zhang… - Phytomedicine, 2023 - Elsevier
Abstract Background Xuanfei Baidu Formula (XBF) is an effective traditional Chinese
medicine (TCM) remedy for treating coronavirus disease 2019 (COVID-19) in China. This …

Involvement of EGF receptor signaling and NLRP12 inflammasome in fine particulate matter‐induced lung inflammation in mice

Y Jin, W Wu, W Zhang, Y Zhao, Y Wu… - Environmental …, 2017 - Wiley Online Library
Epidemiological studies have shown that exposure to ambient fine particulate matter (PM2.
5) is associated with respiratory diseases. Lung inflammation is a central feature of many …

Aspirin attenuates hyperoxia-induced acute respiratory distress syndrome (ARDS) by suppressing pulmonary inflammation via the NF-κB signaling pathway

YT Tung, CH Wei, CC Yen, PY Lee, LB Ware… - Frontiers in …, 2022 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is a common destructive syndrome with high
morbidity and mortality rates. Currently, few effective therapeutic interventions for ARDS are …