A simple complex on the verge of breakdown: isolation of the elusive cyanoformate ion

LJ Murphy, KN Robertson, SG Harroun, CL Brosseau… - Science, 2014 - science.org
Why does cyanide not react destructively with the proximal iron center at the active site of 1-
aminocyclopropane-1-carboxylic acid (ACC) oxidase, an enzyme central to the biosynthesis …

Crystal structure and mechanistic implications of 1-aminocyclopropane-1-carboxylic acid oxidase—the ethylene-forming enzyme

Z Zhang, JS Ren, IJ Clifton, CJ Schofield - Chemistry & biology, 2004 - cell.com
The final step in the biosynthesis of the plant signaling molecule ethylene is catalyzed by 1-
aminocyclopropane-1-carboxylic acid oxidase (ACCO). ACCO requires bicarbonate as an …

Spectroscopic Studies of 1-Aminocyclopropane-1-carboxylic Acid Oxidase:  Molecular Mechanism and CO2 Activation in the Biosynthesis of Ethylene

J Zhou, AM Rocklin, JD Lipscomb, L Que… - Journal of the …, 2002 - ACS Publications
1-Aminocyclopropane-1-carboxylic acid (ACC) oxidase (ACCO) catalyzes the last step in the
biosynthesis of the gaseous plant hormone ethylene, which is involved in development …

Mechanistic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: single turnover reaction

AM Rocklin, K Kato, H Liu, L Que… - JBIC Journal of Biological …, 2004 - Springer
The final step in the biosynthesis of the plant hormone ethylene is catalyzed by the non-
heme iron-containing enzyme 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase …

Inactivation of 1-aminocyclopropane-1-carboxylate oxidase involves oxidative modifications

JN Barlow, Z Zhang, P John, JE Baldwin… - Biochemistry, 1997 - ACS Publications
1-Aminocyclopropane-1-carboxylate (ACC) oxidase catalyzes the final step in the
biosynthesis of the plant signaling molecule ethylene. It is a member of the ferrous iron …

ENDOR studies of the ligation and structure of the non-heme iron site in ACC oxidase

DL Tierney, AM Rocklin, JD Lipscomb… - Journal of the …, 2005 - ACS Publications
Ethylene is a plant hormone involved in all stages of growth and development, including
regulation of germination, responses to environmental stress, and fruit ripening. The final …

Biological formation of ethylene

RP Hausinger, SBJS Rifayee, MG Thomas… - RSC chemical …, 2023 - pubs.rsc.org
This review summarizes the structures, biochemical properties, and mechanisms of two
major biological sources of ethylene, the ethylene-forming enzyme (EFE) and 1 …

The nature of O2 activation by the ethylene-forming enzyme 1-aminocyclopropane-1-carboxylic acid oxidase

LM Mirica, JP Klinman - Proceedings of the National …, 2008 - National Acad Sciences
Ethylene is a plant hormone important in many aspects of plant growth and development
such as germination, fruit ripening, and senescence. 1-Aminocyclopropane-1-carboxylic …

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

FH Vaillancourt, E Yeh, DA Vosburg, SE O'Connor… - Nature, 2005 - nature.com
Enzymatic incorporation of chlorine, bromine or iodine atoms occurs during the biosynthesis
of more than 4,000 natural products. Halogenation can have significant consequences for …

Ethylene biosynthesis: the role of 1‐aminocyclopropane‐1‐carboxylate (ACC) oxidase, and its possible evolutionary origin

P John - Physiologia Plantarum, 1997 - Wiley Online Library
Recent developments in our knowledge of the biochemistry of 1‐aminocyclopropane‐1‐
carboxylate (ACC) oxidase, the enzyme responsible for the final stage in the biosynthesis of …