[HTML][HTML] A comparative transcriptome analysis identifying FGF23 regulated genes in the kidney of a mouse CKD model
B Dai, V David, A Martin, J Huang, H Li, Y Jiao, W Gu… - 2012 - journals.plos.org
Elevations of circulating Fibroblast growth factor 23 (FGF23) are associated with adverse
cardiovascular outcomes and progression of renal failure in chronic kidney disease (CKD) …
cardiovascular outcomes and progression of renal failure in chronic kidney disease (CKD) …
FGF23 from bench to bedside
CP Kovesdy, LD Quarles - American Journal of Physiology …, 2016 - journals.physiology.org
There is a strong association between elevated circulating fibroblast growth factor-23
(FGF23) levels and adverse outcomes in patients with chronic kidney disease (CKD) of all …
(FGF23) levels and adverse outcomes in patients with chronic kidney disease (CKD) of all …
[HTML][HTML] Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease
Patients with chronic kidney disease (CKD) develop increased levels of the phosphate-
regulating hormone, fibroblast growth factor (FGF) 23, that are associated with a higher risk …
regulating hormone, fibroblast growth factor (FGF) 23, that are associated with a higher risk …
[HTML][HTML] FGF23 activates injury-primed renal fibroblasts via FGFR4-dependent signalling and enhancement of TGF-β autoinduction
Bone-derived fibroblast growth factor 23 (FGF23) is an important endocrine regulator of
mineral homeostasis with effects transduced by cognate FGF receptor (FGFR) 1-α-Klotho …
mineral homeostasis with effects transduced by cognate FGF receptor (FGFR) 1-α-Klotho …
[HTML][HTML] Update on fibroblast growth factor 23 in chronic kidney disease
M Wolf - Kidney international, 2012 - Elsevier
Chronic kidney disease (CKD) is a public health epidemic that affects millions of people
worldwide. Presence of CKD predisposes individuals to high risks of end-stage renal …
worldwide. Presence of CKD predisposes individuals to high risks of end-stage renal …
[HTML][HTML] Renal expression of FGF23 and peripheral resistance to elevated FGF23 in rodent models of polycystic kidney disease
D Spichtig, H Zhang, N Mohebbi, I Pavik, K Petzold… - Kidney international, 2014 - Elsevier
Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and is linked to
cardiovascular disease and all-cause mortality in chronic kidney disease. FGF23 rises in …
cardiovascular disease and all-cause mortality in chronic kidney disease. FGF23 rises in …
Regulation and effects of FGF23 in chronic kidney disease
J Musgrove, M Wolf - Annual review of physiology, 2020 - annualreviews.org
Chronic kidney disease (CKD) is a global health epidemic that accelerates cardiovascular
disease, increases risk of infection, and causes anemia and bone disease, among other …
disease, increases risk of infection, and causes anemia and bone disease, among other …
[HTML][HTML] FGF23 induces left ventricular hypertrophy
Chronic kidney disease (CKD) is a public health epidemic that increases risk of death due to
cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …
cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …
FGF23 in chronic kidney disease
P Wahl, M Wolf - Endocrine FGFs and Klothos, 2012 - Springer
Chronic kidney disease (CKD) is a growing public health epidemic that is associated with a
markedly increased risk of cardiovascular mortality. Disordered mineral metabolism and …
markedly increased risk of cardiovascular mortality. Disordered mineral metabolism and …
[HTML][HTML] Increased FGF23 protects against detrimental cardio-renal consequences during elevated blood phosphate in CKD
EL Clinkenbeard, ML Noonan, JC Thomas, P Ni… - JCI insight, 2019 - ncbi.nlm.nih.gov
The phosphaturic hormone FGF23 is elevated in chronic kidney disease (CKD). The risk of
premature death is substantially higher in the CKD patient population, with cardiovascular …
premature death is substantially higher in the CKD patient population, with cardiovascular …