[HTML][HTML] SARS-CoV-2 receptor networks in diabetic and COVID-19–associated kidney disease

R Menon, EA Otto, R Sealfon, V Nair, AK Wong… - Kidney international, 2020 - Elsevier
COVID-19 morbidity and mortality are increased in patients with diabetes and kidney
disease via unknown mechanisms. SARS-CoV-2 uses angiotensin-converting enzyme 2 …

Renal manifestations of Covid-19: physiology and pathophysiology

Z Armaly, S Kinaneh, K Skorecki - Journal of clinical medicine, 2021 - mdpi.com
Corona virus disease 2019 (COVID-19) imposes a serious public health pandemic affecting
the whole world, as it is spreading exponentially. Besides its high infectivity, SARS-CoV-2 …

[HTML][HTML] A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells

E Garreta, P Prado, ML Stanifer, V Monteil, A Marco… - Cell Metabolism, 2022 - cell.com
It is not well understood why diabetic individuals are more prone to develop severe COVID-
19. To this, we here established a human kidney organoid model promoting early hallmarks …

[HTML][HTML] Attenuation of SARS-CoV-2 infection by losartan in human kidney organoids

W Rahmani, H Chung, S Sinha, MP Bui-Marinos… - IScience, 2022 - cell.com
COVID-19-associated acute kidney injury (COVID-AKI) is a common complication of SARS-
CoV-2 infection in hospitalized patients. The susceptibility of human kidneys to direct SARS …

Coronavirus disease (COVID)-19 and diabetic kidney disease

SP Srivastava, R Srivastava, S Chand, JE Goodwin - Pharmaceuticals, 2021 - mdpi.com
The present review describes COVID-19 severity in diabetes and diabetic kidney disease.
We discuss the crucial effect of COVID-19-associated cytokine storm and linked injuries and …

Is the kidney a target of SARS-CoV-2?

MA Martinez-Rojas, O Vega-Vega… - American Journal of …, 2020 - journals.physiology.org
The new disease produced by severe acute respiratory syndrome-coronavirus 2 (SARS-
CoV-2) represents a major pandemic event nowadays. Since its origin in China in …

Single‐cell RNA sequencing analysis of human kidney reveals the presence of ACE2 receptor: A potential pathway of COVID‐19 infection

Q He, TN Mok, L Yun, C He, J Li… - Molecular genetics & …, 2020 - Wiley Online Library
Background A novel coronavirus called SARS‐Cov‐2, which shared 82% similarity of
genome sequence with SARS‐CoV, was found in Wuhan in late December of 2019, causing …

Human kidney spheroids and monolayers provide insights into SARS-CoV-2 renal interactions

D Omer, O Pleniceanu, Y Gnatek… - Journal of the …, 2021 - journals.lww.com
Background Although coronavirus disease 2019 (COVID-19) causes significan t morbidity,
mainly from pulmonary involvement, extrapulmonary symptoms are also major componen ts …

Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney

X Jiang, JM Eales, D Scannali… - European heart …, 2020 - academic.oup.com
Aims Angiotensin-converting enzyme 2 (ACE2) is the cellular entry point for severe acute
respiratory syndrome coronavirus (SARS-CoV-2)—the cause of coronavirus disease 2019 …

Does SARS-CoV-2 infect the kidney?

S Khan, L Chen, CR Yang, V Raghuram… - Journal of the …, 2020 - journals.lww.com
Six recent publications have provided evidence compatible with the conclusion that severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can directly infect the kidney …