Meta-analysis of diabetic nephropathy associated genetic variants in inflammation and angiogenesis involved in different biochemical pathways

N Nazir, K Siddiqui, S Al-Qasim, D Al-Naqeb - BMC medical genetics, 2014 - Springer
Background Diabetes mellitus is the most common chronic endocrine disorder, affecting an
estimated population of 382 million people worldwide. It is associated with microvascular …

A systematic review and meta-analysis of genetic association studies for the role of inflammation and the immune system in diabetic nephropathy

M Tziastoudi, I Stefanidis… - Clinical kidney …, 2017 - academic.oup.com
Background: Despite the certain contribution of metabolic and haemodynamic factors in
diabetic nephropathy (DN), many lines of evidence highlight the role of immunologic and …

Genetic variations in key inflammatory cytokines exacerbates the risk of diabetic nephropathy by influencing the gene expression

I Hameed, SR Masoodi, PA Malik, SA Mir, K Ghazanfar… - Gene, 2018 - Elsevier
Background Diabetic nephropathy is the single strongest predictor of mortality in patients
with diabetes. The development of overt nephropathy involves important inter-individual …

Genetic associations in diabetic nephropathy: a meta-analysis

AL Mooyaart, EJJ Valk, LA Van Es, JA Bruijn… - Diabetologia, 2011 - Springer
Aims/hypothesis This meta-analysis assessed the pooled effect of each genetic variant
reproducibly associated with diabetic nephropathy. Methods PubMed, EMBASE and Web of …

Genetics of diabetic nephropathy in type 2 DM: candidate gene analysis for the pathogenic role of inflammation

SHO LEE, TW Lee, CG IHM, MJ Kim, JT WOO… - …, 2005 - Wiley Online Library
Hypertension, poor glycemic control and albuminuria are well known risk factors for diabetic
nephropathy, but these factors do not explain all of the inter‐individual variabilities in the …

Development of biomarkers and molecular therapy based on inflammatory genes in diabetic nephropathy

AK Maiti - International Journal of Molecular Sciences, 2021 - mdpi.com
Diabetic Nephropathy (DN) is a debilitating consequence of both Type 1 and Type 2
diabetes affecting the kidney and renal tubules leading to End Stage Renal Disease …

The genetic map of diabetic nephropathy: evidence from a systematic review and meta-analysis of genetic association studies

M Tziastoudi, I Stefanidis, E Zintzaras - Clinical kidney journal, 2020 - academic.oup.com
Despite the extensive efforts of scientists, the genetic background of diabetic nephropathy
(DN) has not yet been clarified. To elucidate the genetic variants that predispose to the …

[HTML][HTML] Association of genetic variants with diabetic nephropathy

S Rizvi, ST Raza, F Mahdi - World journal of diabetes, 2014 - ncbi.nlm.nih.gov
Diabetic nephropathy accounts for the most serious microvascular complication of diabetes
mellitus. It is suggested that the prevalence of diabetic nephropathy will continue to increase …

Integrative analyses of biomarkers and pathways for diabetic nephropathy

B Li, X Zhao, W Xie, Z Hong, Y Zhang - Frontiers in Genetics, 2023 - frontiersin.org
Background: Diabetic nephropathy (DN) is a widespread diabetic complication and a major
cause of terminal kidney disease. There is no doubt that DN is a chronic disease that …

The susceptibility genes in diabetic nephropathy

L Wei, Y Xiao, L Li, X Xiong, Y Han, X Zhu, L Sun - Kidney Diseases, 2018 - karger.com
Background: Diabetes mellitus (DM) poses a severe threat to global public health. Diabetic
nephropathy (DN) is one of the most common complications of diabetes and the leading …