Loading microRNA-376c in extracellular vesicles inhibits properties of non-small cell lung cancer cells by targeting YTHDF1

J Zhou, D Xiao, T Qiu, J Li, Z Liu - Technology in Cancer …, 2020 - journals.sagepub.com
Objective: Extracellular vesicles (Evs) secreted from cells have been revealed to mediate
signal transduction between cells. Nevertheless, the mechanisms through which molecules …

[HTML][HTML] LncRNA MIR22HG negatively regulates miR-141-3p to enhance DAPK1 expression and inhibits endometrial carcinoma cells proliferation

Z Cui, X An, J Li, Q Liu, W Liu - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Emerging evidence has indicated that long non-coding RNAs (lncRNAs) play critical roles in
tumor development and progression. Recent studies reported that lncRNA MIR22HG could …

[HTML][HTML] miRNA-708 functions as a tumor suppressor in colorectal cancer by targeting ZEB1 through Akt/mTOR signaling pathway

S Sun, T Hang, B Zhang, L Zhu, Y Wu, X Lv… - American journal of …, 2019 - ncbi.nlm.nih.gov
Background: Colon cancer, or colorectal cancer (CRC), is a type of cancer that develops
from large bowel. Previous data has demonstrated that microRNAs (miRNAs) may be …

[HTML][HTML] MicroRNA-504 functions as a tumor suppressor in hepatocellular carcinoma through inhibiting Frizzled-7-mediated-Wnt/β-catenin signaling

H Quan, B Li, J Yang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Accumulating evidence suggests that microRNAs (miRNAs) are critical regulators in the
development and progression of various malignant tumors, including hepatocellular …

miR-145-5p suppresses proliferation, metastasis and EMT of colorectal cancer by targeting CDCA3

Q Chen, L Zhou, X Ye, M Tao, J Wu - Pathology-Research and Practice, 2020 - Elsevier
MicroRNAs play a critical role in regulating the carcinogenesis of colorectal cancer (CRC).
Even though its role is unclear in CRC, miR-145-5p has been reported to have anti …

The oncogenic role of microRNA-130a/301a/454 in human colorectal cancer via targeting Smad4 expression

L Liu, J Nie, L Chen, G Dong, X Du, X Wu, Y Tang… - PloS one, 2013 - journals.plos.org
Transforming growth factor (TGF)-β/Smad signaling plays an important role in colon cancer
development, progression and metastasis. In this study we demonstrated that the microRNA …

microRNA-202-3p inhibits cell proliferation by targeting ADP-ribosylation factor-like 5A in human colorectal carcinoma

Q Wang, Z Huang, W Guo, S Ni, X Xiao, L Wang… - Clinical Cancer …, 2014 - AACR
Purpose: MicroRNAs (miRNA) that are strongly implicated in carcinogenesis have recently
reshaped our understanding of the role of non–protein-coding RNAs. Here, we focused on …

[PDF][PDF] METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N6‐methyladenosine‐dependent primary MicroRNA processing

J Ma, F Yang, C Zhou, F Liu, J Yuan, F Wang… - …, 2017 - Wiley Online Library
N6‐Methyladenosine (m6A) modification has been implicated in many biological processes.
However, its role in cancer has not been well studied. Here, we demonstrate that m6A …

MicroRNA‐143‐3p inhibits colorectal cancer metastases by targeting ITGA6 and ASAP3

L Guo, J Fu, S Sun, M Zhu, L Zhang, H Niu… - Cancer …, 2019 - Wiley Online Library
MicroRNAs, which regulate mRNAs, operate through a variety of signaling pathways to
participate in the development of colorectal cancer (CRC). In this study, we found that …

Overexpression of microRNA-30a-5p inhibits liver cancer cell proliferation and induces apoptosis by targeting MTDH/PTEN/AKT pathway

W Li, H Dai, Q Ou, G Zuo, C Liu - Tumor Biology, 2016 - Springer
Increasing results suggest microRNAs (miRNAs) could function important roles in malignant
tumor progression. miR-30a-5p is downregulated in variety of cancers and acts as a cancer …