A differentiation roadmap of murine placentation at single-cell resolution
The placenta is one of the most important yet least understood organs. Due to the limitations
of conventional research approaches, we are still far from a comprehensive understanding …
of conventional research approaches, we are still far from a comprehensive understanding …
The placenta: epigenetic insights into trophoblast developmental models of a generation-bridging organ with long-lasting impact on lifelong health
M Hemberger, W Dean - Physiological Reviews, 2023 - journals.physiology.org
The placenta is a unique organ system that functionally combines both maternal and fetal
cell types with distinct lineage origins. Normal placentation is critical for developmental …
cell types with distinct lineage origins. Normal placentation is critical for developmental …
Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta
The placenta is crucial for a successful pregnancy and the health of both the fetus and the
pregnant woman. However, how the human trophoblast lineage is regulated, including the …
pregnant woman. However, how the human trophoblast lineage is regulated, including the …
Single-cell RNA-seq revealed diverse cell types in the mouse placenta at mid-gestation
X Zhou, Y Xu, S Ren, D Liu, N Yang, Q Han… - Experimental Cell …, 2021 - Elsevier
The mammalian placenta consists of a set of cells to ensure normal placental functions
throughout gestation. Dysfunctional placentae are considered as the origin of a series of …
throughout gestation. Dysfunctional placentae are considered as the origin of a series of …
A single-cell survey of the human first-trimester placenta and decidua
H Suryawanshi, P Morozov, A Straus… - Science …, 2018 - science.org
The placenta and decidua interact dynamically to enable embryonic and fetal development.
Here, we report single-cell RNA sequencing of 14,341 and 6754 cells from first-trimester …
Here, we report single-cell RNA sequencing of 14,341 and 6754 cells from first-trimester …
Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development
An increasing body of evidence points to significant spatio-temporal differences in early
placental development between mouse and human, but a detailed comparison of placentae …
placental development between mouse and human, but a detailed comparison of placentae …
Isolation and characterisation of a novel trophoblast side-population from first trimester placentae
JL James, DG Hurley, T Gamage, T Zhang… - …, 2015 - rep.bioscientifica.com
The placenta is responsible for all nutrient and gas exchange between mother and baby
during pregnancy. The differentiation of specialised placental epithelial cells called …
during pregnancy. The differentiation of specialised placental epithelial cells called …
Development of the human placenta
MY Turco, A Moffett - Development, 2019 - journals.biologists.com
The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …
placental formation underpins common pregnancy disorders such as pre-eclampsia and …
Unique features and emerging in vitro models of human placental development
Background The placenta is an essential organ for the normal development of mammalian
fetuses. Most of our knowledge on the molecular mechanisms of placental development has …
fetuses. Most of our knowledge on the molecular mechanisms of placental development has …
Mechanisms of early placental development in mouse and humans
The importance of the placenta in supporting mammalian development has long been
recognized, but our knowledge of the molecular, genetic and epigenetic requirements that …
recognized, but our knowledge of the molecular, genetic and epigenetic requirements that …