Human genome editing in clinical applications: Japanese lay and expert attitudes

T Sawai, T Hatta, K Akatsuka, M Fujita - Frontiers in Genetics, 2023 - frontiersin.org
Background: The world's first gene-edited babies, reported by the Chinese scientist He
Jiankui, prompted an outcry of criticism and concerns worldwide over the use of genome …

Genome editing of human embryos for research purposes: Japanese lay and expert attitudes

K Akatsuka, T Hatta, T Sawai, M Fujita - Frontiers in Genetics, 2023 - frontiersin.org
Background: Multiple surveys of the general public and experts on human genome editing
have been conducted. However, many focused only on editing in clinical applications, with …

Public attitudes in the clinical application of genome editing on human embryos in Japan: a cross-sectional survey across multiple stakeholders

S Kobayashi, T Miyoshi, T Kobayashi… - Journal of human …, 2022 - nature.com
Recent advances in genome editing technology are accompanied by increasing public
expectations on its potential clinical application, but there are still scientific, ethical, and …

Statement from the Organizing Committee on Reported Human Embryo Genome Editing

M Galvin - 2018 - nationalacademies.org
HONG KONG--On the eve of the Second International Summit on Human Genome Editing,
we were informed of the birth of twins in China whose embryonic genomes had been edited …

Survey on the perception of germline genome editing among the general public in Japan

M Uchiyama, A Nagai, K Muto - Journal of human genetics, 2018 - nature.com
Genome editing of human embryos could become a fundamental treatment approach for
genetic diseases; however, a few technical and ethical issues need to be resolved before its …

Recent developments in the regulation of heritable human genome editing

S Soni - Journal of Bioethical Inquiry, 2024 - Springer
Abstract In 2018, the Chinese scientist He Jiankui presented his research at the Second
International Summit on Human Genome Editing in Hong Kong. While it was intended that …

Playing it safe? Precaution, risk, and responsibility in human genome editing

S Chan - Perspectives in Biology and Medicine, 2020 - muse.jhu.edu
Human germline genetic modification has long been a controversial topic. Until recently it
remained largely a hypothetical debate: whether one accepted or opposed the idea in …

Regulations on genome editing of human embryos in Japan: Our moral moratorium

E Nakazawa, K Yamamoto, A Akabayashi… - … of Healthcare Ethics, 2018 - cambridge.org
The use of human embryos in genome editing research has recently been approved in
China and the United Kingdom. In Japan, the debate on regulations on genome editing …

Attitudes of clinical geneticists and certified genetic counselors to genome editing and its clinical applications: a nation-wide questionnaire survey in Japan

I Taguchi, T Yamada, R Akaishi, I Imoto… - Journal of Human …, 2019 - nature.com
Genome editing of the human embryo using CRISPR/Cas9 has the potential to prevent
hereditary diseases from being transmitted to the next generation. However, attitudes to this …

One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans

HC Howard, CG van El, F Forzano… - European Journal of …, 2018 - nature.com
Gene editing, which allows for specific location (s) in the genome to be targeted and altered
by deleting, adding or substituting nucleotides, is currently the subject of important academic …